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人 MESDC2 基因ORF全长cDNA克隆(表达载体)

    产品数据评论相关产品实验方法
     MESDC2 cDNA Clone产品信息
    NCBI注册码:NM_015154.1
    参考序列ORF长度:705bp
    cDNA基因描述:Full length Clone DNA of Homo sapiens mesoderm development candidate 2.
    分子别称:BOCA, MESD, KIAA0081
    分子种属:Human
    载体:pCMV3-untagged
    质粒:
    限制性酶切位点:
    Tag序列:
    序列信息:
    测序引物:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
    ( We provide with MESDC2 qPCR primers for gene expression analysis, HP100826 )
    启动子:Enhanced CMV mammalian cell promoter
    Application:Stable or Transient mammalian expression
    抗生素(大肠杆菌):Ampicillin
    抗生素(哺乳动物细胞):Hygromycin
    运输方式:Each tube contains lyophilized plasmid.
    储存方法:The lyophilized plasmid can be stored at room temperature for three months.
    Product nameProduct name
    研究背景

    LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61 and MESDC2, is a member of the MESD family. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity resides in the N- and C-terminal unstructured regions. MESDC2 acts as a modulator of the Wnt pathway, since some LDLRs are coreceptors for the canonical Wnt pathway. MESDC2 is essential for specification of embryonic polarity and mesoderm induction.

    参考资料
  • Scanlan M.J. et al., 1999, Int. J. Cancer 83:456-464.
  • Veltman,IM. et al.,2005, Hum Mol Genet  14 (14):1955-63.
  • Koduri V. et al., 2007, Biochemistry 46:6570-7.
  • Size / Price
    货号: HG10949-UT
    目录价: 
    单价:      (You Save: )

    Datasheet & Documentation

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    请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”