PLA2G2A cDNA ORF Clone, Human, untagged

Cat: HG11187-UT
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PLA2G2A cDNA ORF Clone, Human, untagged 基本信息
基因
种属
Human
NCBI 参考序列号
参考序列ORF长度
435 bp
序列描述
Identical with the Gene Bank Ref. ID sequence except for the point mutation 96 G/C not causing the amino acid variation.
描述
Full length Clone DNA of Human phospholipase A2, group IIA (platelets, synovial fluid).
质粒
启动子
Enhanced CMV promoter
限制性酶切位点
KpnI + XbaI (6.1kb + 0.44kb)
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
抗生素(大肠杆菌)
Ampicillin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.
PLA2G2A cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

PLA2G2A cDNA ORF Clone, Human, untagged Validated Images
other Green fluorescent protein / GFP Gene Plasmid Map 5613
PLA2G2A cDNA ORF Clone, Human, untagged Alternative Names
MOM1 cDNA ORF Clone, Human;PLA2 cDNA ORF Clone, Human;PLA2B cDNA ORF Clone, Human;PLA2L cDNA ORF Clone, Human;PLA2S cDNA ORF Clone, Human;PLAS1 cDNA ORF Clone, Human;sPLA2 cDNA ORF Clone, Human
PLA2G2A Background Information

Phospholipase A2, membrane associated, also known as Phosphatidylcholine 2-acylhydrolase 2A, Group IIA phospholipase A2, Non-pancreatic secretory phospholipase A2 and PLA2G2A, is a peripheral membrane protein which belongs to the phospholipase A2 family. PLA2G2A is found in many cells and also extracellularly. The membrane-bound and secreted forms of PLA2G2A are identical. PLA2G2A has been proposed to play a role in anti-bacterial defense, inflammation and eicosanoid generation, in clearance of apoptotic cells, and in the Wnt signaling pathway. PLA2G2A is thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. PLA2G2A catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. PLA2G2A might be a factor in human colorectal tumorigenesis.

Full Name
phospholipase A2, group IIA (platelets, synovial fluid)
References
  • Praml,C. et al., 1998, Oncogene. 17 (15):2009-12.
  • Fijneman,R.J. et al., 2008,Front Biosci 13 :4144-74.
  • Fijneman,R.J. et al., 2009, Cell Oncol  31 (5):345-56.
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