SILV cDNA ORF Clone, Human, N-DDK (Flag®) tag

Cat: HG13693-NF

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SILV cDNA ORF Clone, Human, N-DDK (Flag®) tag 基本信息

基因

种属
Human
NCBI 参考序列号
参考序列ORF长度
1986 bp
描述
Full length Clone DNA of Human premelanosome protein with N terminal Flag tag.

质粒

启动子
Enhanced CMV promoter
标签序列
FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.

筛选

抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression

储存 & 运输

运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

关于 SILV的更多信息

Entrez Gene ID

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

SILV cDNA ORF Clone, Human, N-DDK (Flag®) tag Alternative Names

D12S53E cDNA ORF Clone, Human;gp100 cDNA ORF Clone, Human;ME20 cDNA ORF Clone, Human;ME20-M cDNA ORF Clone, Human;ME20M cDNA ORF Clone, Human;P1 cDNA ORF Clone, Human;P100 cDNA ORF Clone, Human;PMEL17 cDNA ORF Clone, Human;SI cDNA ORF Clone, Human;SIL cDNA ORF Clone, Human;SILV cDNA ORF Clone, Human

SILV Background Information

SILV gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
premelanosome protein
References
  • Eich C, Lasonder E, Cruz LJ, et al. Proteome Based Construction of the Lymphocyte Function-Associated Antigen 1 (LFA-1) Interactome in Human Dendritic Cells. Mattei F, ed. PLoS ONE. 2016;11(2):e0149637.
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