BIT1 cDNA ORF Clone, Human, C-DDK (Flag®) tag

Cat: HG13645-CF

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BIT1 cDNA ORF Clone, Human, C-DDK (Flag®) tag 基本信息

基因

种属
Human
NCBI 参考序列号
参考序列ORF长度
540 bp
描述
Full length Clone DNA of Human peptidyl-tRNA hydrolase 2 with C terminal Flag tag.

质粒

启动子
Enhanced CMV promoter
载体
标签序列
FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.

筛选

抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression

储存 & 运输

运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

BIT1 cDNA ORF Clone, Human, C-DDK (Flag®) tag Alternative Names

BIT1 cDNA ORF Clone, Human;CFAP37 cDNA ORF Clone, Human;CGI-147 cDNA ORF Clone, Human;IMNEPD cDNA ORF Clone, Human;PTH cDNA ORF Clone, Human;PTH 2 cDNA ORF Clone, Human;PTH2 cDNA ORF Clone, Human;PTRH2 cDNA ORF Clone, Human

BIT1 Background Information

PTH2, also known as PTRH2, is a mitochondrial protein which belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. When in the cytoplasm, PTRH2 regulates the function of 2 transcriptional regulators, TLE5 and TLE1, thus promoting caspase-independent cell death.

Full Name
peptidyl-tRNA hydrolase 2
References
  • Prahalad AK. et al., 2006, Proteomics. 6 (12): 3482-93.
  • Jin L. et al., 2000, J Biol Chem. 275 (35): 27238-44.
  • Boone T. et al., 2000, Nat Struct Biol. 7 (6): 486-91.
  • info info
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