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人 SDF-2/SDF2 基因ORF全长cDNA克隆(表达载体)

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Human SDF2 cDNA Clone产品信息
NCBI注册码:NM_006923.2
参考序列ORF长度:636bp
cDNA基因描述:Full length Clone DNA of Homo sapiens stromal cell-derived factor 2.
分子别称:SDF2
分子种属:Human
载体:pCMV3-untagged
质粒:pCMV3-SDF2
限制性酶切位点:KpnI + XbaI (6.1kb + 0.64kb)
Tag序列:
序列信息:Identical with the Gene Bank Ref. ID sequence.
测序引物:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
启动子:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
抗生素(大肠杆菌):Ampicilin
抗生素(哺乳动物细胞):Hygromycin
运输方式:Each tube contains lyophilized plasmid.
储存方法:The lyophilized plasmid can be stored at room temperature for three months.
Human SDF2 基因质粒图
Human SDF2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged
Product nameProduct name
研究背景

Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 and SDF-5 are not well defined and their biological functions are less known. SDF-2 is first isolated from the mouse stromal cell line ST2 as a secretory protein. The amino acid sequence deduced from the murine clone and the human homolog are conserved more than 92 %, and the aa sequence of SDF-2 shows similarity to those of yeast dolichyl phosphate-D-mannose, protein mannosyltransferases. SDF-1 and its receptor are strongly indicated in the progression of various cancers including breast cancer. SDF-2, SDF2-L1, SDF-4, and SDF-5 are ubiquitously expressed in various cancer cell lines and SDF-2, SDF-4 and SDF-5 are expressed in mammary tissues. These SDFs have prognostic value and warrant further investigation in their biological functions and clinical value.

参考资料
  • Hamada,T.etal.,1996,Gene.176(1-2):211-214.
  • Anjard,C.etal.,1998,Development.125(20):4067-4075.
  • Kang,H.etal.,2009,Int J Oncol.35(1):205-211. 
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    货号: HG10950-UT
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    • Human SDF2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged
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