( We provide with TNFRSF25 qPCR primers for gene expression analysis, HP101623 )
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|人 TNFRSF25/DR3/TNFRSF12 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签||HG12095-ACG|
|人 TNFRSF25/DR3/TNFRSF12 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签||HG12095-ACR|
|人 TNFRSF25/DR3/TNFRSF12 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||HG12095-CF|
|人 TNFRSF25/DR3/TNFRSF12 基因ORF全长cDNA克隆(表达载体), C-His 标签||HG12095-CH|
|人 TNFRSF25/DR3/TNFRSF12 基因ORF全长cDNA克隆(表达载体), C-Myc 标签||HG12095-CM|
|人 TNFRSF25/DR3/TNFRSF12 基因ORF全长cDNA克隆(表达载体), C-HA 标签||HG12095-CY|
|人 TNFRSF25/DR3/TNFRSF12 基因ORF全长cDNA(克隆载体)||HG12095-G|
|人 TNFRSF25/DR3/TNFRSF12 基因ORF全长cDNA克隆(表达载体), N-Flag 标签||HG12095-NF|
|人 TNFRSF25/DR3/TNFRSF12 基因ORF全长cDNA克隆(表达载体), N-His 标签||HG12095-NH|
|人 TNFRSF25/DR3/TNFRSF12 基因ORF全长cDNA克隆(表达载体), N-Myc 标签||HG12095-NM|
|人 TNFRSF25/DR3/TNFRSF12 基因ORF全长cDNA克隆(表达载体), N-HA 标签||HG12095-NY|
|人 TNFRSF25/DR3/TNFRSF12 基因ORF全长cDNA克隆(表达载体)||HG12095-UT|
Tumor necrosis factor receptor superfamily, member 25 (TNFRSF25), also known as Death receptor 3 (DR3) or TNFRSF12 is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. TNFRSF25/DR3/TNFRSF12 has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this TNFRSF25 encoding gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.