E1 Ubiquitin Activating Enzyme qPCR Primer Pairs, Human

Cat: HP101533

Contact us:

215-583-7898
order@sinobiological.com
Distributors

All E1 Ubiquitin Activating Enzyme Reagents

CRO Services

Product recommended


All E1 Ubiquitin Activating Enzyme Reagents

E1 Ubiquitin Activating Enzyme qPCR Primer Pairs, Human 基本信息

Target Details

种属:
Human

Product Details

Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.

Application & Quality

应用:
SYBR® Green-based quantitative real-time PCR (qPCR).
质控:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.

储存 & 运输

运输:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
储存:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages

Unique Primer Design

To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.

Strict Validation Process

Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.

Uniform PCR conditions, Saving time and cost

~100% amplification curve, ensuring the accuracy of the RNA quantitative

E1 Ubiquitin Activating Enzyme qPCR Primer Pairs, Human Alternative Names

A1S9 qPCR Primer Pairs, Human;A1S9T qPCR Primer Pairs, Human;A1ST qPCR Primer Pairs, Human;AMCX1 qPCR Primer Pairs, Human;CFAP124 qPCR Primer Pairs, Human;CTD-2522E6.1 qPCR Primer Pairs, Human;GXP1 qPCR Primer Pairs, Human;POC20 qPCR Primer Pairs, Human;SMAX2 qPCR Primer Pairs, Human;UBA1A qPCR Primer Pairs, Human;UBE1 qPCR Primer Pairs, Human;UBE1X qPCR Primer Pairs, Human

E1 Ubiquitin Activating Enzyme Background Information

UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It also catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Defects in UBA1 can cause spinal muscular atrophy X-linked type 2 (SMAX2), also known as X-linked lethal infantile spinal muscular atrophy, distal X-linked arthrogryposis multiplex congenita or X-linked arthrogryposis type 1 (AMCX1). Spinal muscular atrophy refers to a group of neuromuscular disorders characterized by degeneration of the anterior horn cells of the spinal cord, leading to symmetrical muscle weakness and atrophy. SMAX2 is a lethal infantile form presenting with hypotonia, areflexia, and multiple congenital contractures.

Full Name
ubiquitin-like modifier activating enzyme 1
References
  • Jin J, et al. (2007) Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging. Nature. 447(7148):1135-8.
  • Xia T, et al. (2007) Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclase. Am J Physiol Heart Circ Physiol. 293(5):H3080-7.
  • Pridgeon JW, et al. (2009) Proteomic analysis reveals Hrs UIM-mediated ubiquitin signaling in multiple cellular processes. FEBS J. 276(1):118-31.
  • E1 Ubiquitin Activating Enzyme qPCR Primer Pairs, Cynomolgus, Related Products

    Product Name Catalog#(PDF)
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone in Cloning Vector, Cynomolgus CG90821-G
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, untagged CG90821-UT
    E1 Ubiquitin Activating Enzyme Lentiviral cDNA ORF Clone, Cynomolgus, C-GFPSpark® tag CG90821-ACGLN
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, C-GFPSpark® tag CG90821-ACG
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, N-GFPSpark® tag CG90821-ANG
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, C-OFPSpark® tag CG90821-ACR
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, N-OFPSpark® tag CG90821-ANR
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, C-DDK (Flag®) tag CG90821-CF
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, N-DDK (Flag®) tag CG90821-NF
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, C-His tag CG90821-CH
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, N-His tag CG90821-NH
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, C-HA tag CG90821-CY
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, N-HA tag CG90821-NY
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, C-Myc tag CG90821-CM
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Cynomolgus, N-Myc tag CG90821-NM

    E1 Ubiquitin Activating Enzyme qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone in Cloning Vector, Mouse MG53774-U
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, untagged MG53774-UT
    E1 Ubiquitin Activating Enzyme Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG53774-ACGLN
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, C-GFPSpark® tag MG53774-ACG
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, N-GFPSpark® tag MG53774-ANG
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, C-OFPSpark® tag MG53774-ACR
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, N-OFPSpark® tag MG53774-ANR
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG53774-CF
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG53774-NF
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, C-His tag MG53774-CH
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, N-His tag MG53774-NH
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, C-HA tag MG53774-CY
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, N-HA tag MG53774-NY
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, C-Myc tag MG53774-CM
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Mouse, N-Myc tag MG53774-NM

    E1 Ubiquitin Activating Enzyme qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone in Cloning Vector, Human HG11990-U
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Human, C-GFPSpark® tag HG11990-ACG
    E1 Ubiquitin Activating Enzyme Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG11990-ACGLN
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Human, C-DDK (Flag®) tag HG11990-CF
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Human, N-DDK (Flag®) tag HG11990-NF
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Human, C-His tag HG11990-CH
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Human, C-HA tag HG11990-CY
    E1 Ubiquitin Activating Enzyme cDNA ORF Clone, Human, C-Myc tag HG11990-CM
    info info
    添加购物车成功! 添加购物车失败!