全文搜索服务由Google提供。搜索操作不会离开我们的网站。请放心操作。Google
ICOSL/ICOS ligand/B7-h2
蛋白，抗体，试剂盒，cDNA克隆
表达宿主: Human Cells |   |
表达宿主: Human Cells | |
表达宿主: Human Cells | |
表达宿主: Human Cells | |
-MM01-FITC-PE-APC-RPMI8226.png)
-R101-FITC-RPMI8226.png)
-MM01-Purified-RPMI8226.png)
ICOSL/ICOS ligand/B7-h2 相关研究领域
ICOSL/ICOS ligand/B7-h2 相关信号通路
ICOSL/ICOS ligand/B7-h2 相关蛋白、抗体、cDNA基因、ELISA试剂盒
ICOSL/ICOS ligand/B7-h2 相关蛋白、抗体、cDNA基因、ELISA试剂盒
ICOSL/ICOS ligand/B7-h2 研究背景
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
General information above from UniProt
Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains, and binds to ICOS on activated T cells, thus delivers a positive costimulatory signal for optimal T cell function. The structural features of ICOSL are crucial for its costimulatory function. Present study shows that ICOSL displays a marked oligomerization potential, resembling more like B7-1 than B7-2. B7-H2-dependent signaling may play an active role in a proliferative response rather than in cytokine and chemokine production. The CD28/B7 and ICOS/B7-H2 pathways are both critical for costimulating T cell immune responses. Deficiency in either pathway results in defective T cell activation, cytokine production and germinal center formation.
Immune Checkpoint
Immune Checkpoint Detection: Antibodies Immune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: FCM Antibodies Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Targets Co-stimulatory Immune Checkpoint Targets
ICOSL/ICOS ligand/B7-h2 别称
ICOSL/ICOS ligand/B7-h2 相关文献
请注意：所有产品都是“仅用于科研，而不能用于诊断或治疗用途”
