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IL-11 / interleukin 11  蛋白,抗体,试剂盒,cDNA克隆

表达宿主: E. coli  
  • Slide 1
  • Slide 1
12225-HNCE-50
12225-HNCE-5
12225-HNCE-20
12225-HNCE-10
50 µg 
5 µg 
20 µg 
10 µg 
Add to Cart
表达宿主: E. coli  
  • Slide 1
50117-MNCE-50
50117-MNCE-5
50117-MNCE-100
50117-MNCE-10
50 µg 
5 µg 
100 µg 
10 µg 
Add to Cart

IL-11 / interleukin 11 相关研究领域

IL-11 / interleukin 11 相关信号通路

    IL-11 / interleukin 11 相关蛋白、抗体、cDNA基因、ELISA试剂盒

    IL-11 / interleukin 11 相关蛋白、抗体、cDNA基因、ELISA试剂盒

    IL-11 / interleukin 11 概述&蛋白信息

    IL-11 / interleukin 11 研究背景

    亚单位结构: Interacts with IL6ST and either IL11RA1 or IL11RA2, giving rise to a multimeric signaling complex. {ECO:0000269|PubMed:12919066, ECO:0000305|PubMed:12919066}.
    亚细胞定位: Secreted {ECO:0000269|PubMed:1828438, ECO:0000269|PubMed:2145578}.
    相似的序列: Belongs to the IL-6 superfamily. {ECO:0000305}.
    General information above from UniProt

    IL11 is a multifunctional cytokine first isolated in 1990 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation and could be use as a therapeutic for osteoporosis. IL11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation and to some extent of decidualization.

    IL-11 / interleukin 11 别称

    AGIF,IL-11, [homo-sapiens]
    interleukin 11,IL11,AGIF,IL-11,adipogenesis inhibitory factor,oprelvekin, [human]
    interleukin 11,Il11,IL-11, [mouse]
    IL-11, [mus-musculus]

    IL-11 / interleukin 11 相关文献

  • McKinley D. et al., 1992, Genomics. 13 (3): 814-9.
  • Paul SR. et al., 1990, Proc Natl Acad Sci. 87 (19): 7512-6.
  • Kawashima I. et al., 1991, FEBS Lett. 283 (2): 199-202.
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