All IL17 reagents are produced in house and quality controlled, including 8 IL17 Antibody, 4 IL17 ELISA, 81 IL17 Gene, 3 IL17 Lysate, 12 IL17 Protein, 3 IL17 qPCR. All IL17 reagents are ready to use.
Recombinant IL17 proteins are expressed by E. coli, Baculovirus-Insect Cells, Yeast, CHO Stable Cells with fusion tags as Native, N-His.
IL17antibodies are validated with different applications, which are ELISA, ELISA(Det), ELISA(Cap), Neutralization.
IL17cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL17 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
IL17ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
IL17, also known as IL17a, is a cytokine belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. The IL-17 family of cytokines includes six members, IL-17/IL-17A, IL-17B, IL-17C, IL-17D, IL-17E/IL-25, and IL-17F, which are produced by multiple cell types. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.