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野猪 IL1B / IL-1 beta 蛋白

  • IL1B protein SDS-PAGE
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野猪 IL1B 蛋白产品信息
分子别称:IL1B, IL-1 beta
蛋白构建:A DNA sequence encoding the sus scrofa IL1B (NP_999220.1) (Ala115-Pro267) was expressed with an initial Met.
分子种属:Sus scrofa (Pig)
表达宿主:E. coli
运输说明:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
野猪 IL1B 蛋白质控检测
纯度:> 90 % as determined by SDS-PAGE.
生物活性:Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. Symons,J.A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens,M.J. et al. (eds): IRL Press. 272.
The ED50 for this effect is typically 0.08-0.4 ng/mL.
内毒素:Please contact us for more information.
稳定性:Samples are stable for up to twelve months from date of receipt at -70℃
预测N端:Met
分子量:The recombinant sus scrofa IL1B consists 154 amino acids and predicts a molecular mass of 17.7 kDa.
缓冲液:Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
野猪 IL1B 蛋白使用指导
储存方法:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
复溶条件:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
野猪 IL1B 蛋白SDS-PAGE
IL1B protein SDS-PAGE

IL1B 相关信号通路

Other IL1B 蛋白 Products
IL1B/IL-1B/IL-1 beta 研究背景

Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

野猪 IL1B/IL-1B/IL-1 beta 参考资料
  • Kim SH, et al. (2008) Association of -31TC and -511 CT polymorphisms in the interleukin 1 beta (IL1B) promoter in Korean keratoconus patients. Mol Vis. 14:2109-16.
  • Wang ZC, et al. (2002) T helper 1-type immunity to trophoblast antigens in women with a history of recurrent pregnancy loss is associated with polymorphism of the IL1B promoter region. Genes Immun. 3(1): 38-42.
  • Mattuzzi S, et al. (2007) Association of polymorphisms in the IL1B and IL2 genes with susceptibility and severity of systemic sclerosis. J Rheumatol. 34(5): 997-1004.
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    货号: 62003-WNAE-20
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