TIM-1 / KIM-1 (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)
All TIM-1 / KIM-1 reagents are produced in house and quality controlled, including 27 TIM-1 / KIM-1 Antibody, 4 TIM-1 / KIM-1 ELISA, 52 TIM-1 / KIM-1 Gene, 13 TIM-1 / KIM-1 Lysate, 13 TIM-1 / KIM-1 Protein, 3 TIM-1 / KIM-1 qPCR. All TIM-1 / KIM-1 reagents are ready to use.
All TIM-1 / KIM-1 Reagents
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TIM-1 / KIM-1 Protein (13)Recombinant TIM-1 / KIM-1 proteins are expressed by HEK293 Cells with fusion tags as N-His, N-human IgG1-Fc & C-His, C-His, N-cleavage, N-mouse IgG1-Fc.
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TIM-1 / KIM-1 Antibody (27)TIM-1 / KIM-1 antibodies are validated with different applications, which are ELISA(Det), ELISA, ELISA(Cap), WB, IP, IHC-P.
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TIM-1 / KIM-1 ELISA Kit (4)TIM-1 / KIM-1 ELISA Kits are quality controlled by 8 internation QC standards which guarantee every ELISA Kit with high quality.
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TIM-1 / KIM-1 Lysate (13)TIM-1 / KIM-1 overexpression lysate was created in HEK293 Cells and intented for use as a Western blot (WB) positive control. Purification of TIM-1 / KIM-1 protein from the overexpression lysate was verified.
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TIM-1 / KIM-1 cDNA Clone (52)TIM-1 / KIM-1 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each TIM-1 / KIM-1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
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TIM-1 / KIM-1 qPCR Primer (3)Verified forward and reverse primers for analyzing the quantitative expression of gene. The primer mix has been verified to generate satisfactory qPCR data on Roche LightCycler480.
TIM-1 / KIM-1 Protein (13)
TIM-1 / KIM-1 Antibody (27)
TIM-1 / KIM-1 ELISA 试剂盒（即用型）& ELISA 抗体对套装（非即用型）(4)
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线性范围: 43.75 pg/ml
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线性范围: 18.75 pg/ml
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灵敏度: 69 pg/mL
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线性范围: 125 pg/ml
TIM-1 / KIM-1 cDNA Clone (52)
AF043724.1
克隆载体 cDNA 产品
In expression vector
In lentiviral vector
NM_134248.1
克隆载体 cDNA 产品
In expression vector
In lentiviral vector
NM_173149.1
克隆载体 cDNA 产品
In expression vector
In lentiviral vector
NM_001205114.1
克隆载体 cDNA 产品
In expression vector
In lentiviral vector
TIM-1 / KIM-1 qPCR Primer (3)
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TIM-1 / KIM-1 qPCR Primer Pairs, Rat RP300003
TIM-1 / KIM-1 Lysate (13)
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TIM-1 / KIM-1 相关研究领域
TIM-1 / KIM-1 分子背景
HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â… integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
TIM-1 / KIM-1 参考文献
- Tami C, et al. (2007) Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions. J Virol. 81(7): 3437-46.
- Rees AJ, et al. (2008) Kim-1/Tim-1: from biomarker to therapeutic target? Nephrol Dial Transplant. 23(11): 3394-6.
- Chaturvedi S, et al. (2009) Assay validation for KIM-1: human urinary renal dysfunction biomarker. Int J Biol Sci. 5(2): 128-34.
