KIR2DL3 cDNA ORF Clone in Cloning Vector, Human

Cat: HG12828-G
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KIR2DL3 cDNA ORF Clone in Cloning Vector, Human 基本信息
基因
种属
Human
NCBI 参考序列号
参考序列ORF长度
1026 bp
序列描述
Identical with the Gene Bank Ref. ID sequence except for the point mutation 16 G/A resulting in the amino acid Val substitution by Ile.
描述
Full length Clone DNA of Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3.
质粒
载体
pGEM-T Vector
测序引物
SP6 and T7 or M13-47 and RV-M
质控
The plasmid is confirmed by full-length sequencing.
筛选
抗生素(大肠杆菌)
Ampicillin
储存 & 运输
运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.
KIR2DL3 cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

KIR2DL3 cDNA ORF Clone in Cloning Vector, Human Alternative Names
CD158b cDNA ORF Clone, Human;CD158B2 cDNA ORF Clone, Human;CU464054.1 cDNA ORF Clone, Human;GL183 cDNA ORF Clone, Human;KIR-023GB cDNA ORF Clone, Human;KIR-K7b cDNA ORF Clone, Human;KIR-K7c cDNA ORF Clone, Human;KIR2DS5 cDNA ORF Clone, Human;KIRCL23 cDNA ORF Clone, Human;MGC129943 cDNA ORF Clone, Human;NKAT cDNA ORF Clone, Human;NKAT2 cDNA ORF Clone, Human;NKAT2A cDNA ORF Clone, Human;NKAT2B cDNA ORF Clone, Human;p58 cDNA ORF Clone, Human
KIR2DL3 Background Information

Killer cell immunoglobulin-like receptor 2DL3, also known as CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily. KIR2DL3 contains 2 Ig-like C2-type (immunoglobulin-like) domains. KIR2DL3 interacts with ARRB2. KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). KIR2DL3 inhibits the activity of NK cells thus preventing cell lysis.

Full Name
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
References
  • Selvakumar A., et al., 1997, Immunol. Rev. 155:183-196.
  • Wilson M.J., et al., 1997, Tissue Antigens 49:574-579.
  • Maenaka K., et al., 1999, Structure 7:391-398.
  • Vitale,M. et al., 2004, Int Immunol. 16 (10):1459-66.
  • Yu M.-C., et al., 2008, Nat. Immunol. 9:898-907.
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