MMP-8 (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)

All MMP-8 reagents are produced in house and quality controlled, including 9 MMP-8 Antibody, 2 MMP-8 ELISA, 28 MMP-8 Gene, 4 MMP-8 Lysate, 4 MMP-8 Protein, 2 MMP-8 qPCR. All MMP-8 reagents are ready to use.

MMP-8 Protein (4)

MMP-8 Antibody (9)

MMP-8 ELISA 试剂盒(即用型)& ELISA 抗体对套装(非即用型)(2)

MMP-8 cDNA Clone (28)

NM_002424.2

克隆载体 cDNA 产品

In lentiviral vector

NM_008611.4

克隆载体 cDNA 产品

In lentiviral vector

MMP-8 Lysate (4)

MMP-8 分子背景

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases and tumor invasion. Neutrophil collagenase, also known as Matrix metalloproteinase-8, MMP-8, and CLG1, is a member of the peptidase M1A family. MMP-8 may affect the metastatic behaviour of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumour may have a protective effect against lymph node metastasis. MMP-8 may affect the metastatic behaviour of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 participates in wound repair by contributing to the resolution of inflammation and open the possibility to develop new strategies for treating wound healing defects.

MMP-8 参考文献

  • Hasty K.A., et al.,(1990), Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases. J. Biol. Chem. 265:11421-11424.
  • Blaeser J., et al., (1991), Mercurial activation of human polymorphonuclear leucocyte procollagenase.Eur. J. Biochem. 202:1223-1230.
  • Blaeser J., et al.,(1991), Mercurial activation of human polymorphonuclear leucocyte procollagenase. Eur. J. Biochem. 202:1223-1230.