MCP-1 / CCL2 cDNA ORF Clone, Mouse, C-Myc tag 基本信息
基因
序列描述
Identical with the Gene Bank Ref. ID sequence.
描述
Full length Clone DNA of Mouse chemokine (C-C motif) ligand 2 with C terminal Myc tag.
质粒
启动子
Enhanced CMV promoter
限制性酶切位点
KpnI + XbaI (6kb + 0.49kb)
标签序列
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
应用
Stable or Transient mammalian expression
储存 & 运输
运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
MCP-1 / CCL2 cDNA ORF Clone, Mouse, C-Myc tag Validated Images
MCP-1 / CCL2 cDNA ORF Clone, Mouse, C-Myc tag Alternative Names
AI323594 cDNA ORF Clone, Mouse;HC11 cDNA ORF Clone, Mouse;JE cDNA ORF Clone, Mouse;MCAF cDNA ORF Clone, Mouse;MCP-1 cDNA ORF Clone, Mouse;MCP1 cDNA ORF Clone, Mouse;Scya2 cDNA ORF Clone, Mouse;Sigje cDNA ORF Clone, Mouse;SMC-CF cDNA ORF Clone, Mouse
MCP-1 / CCL2 Background Information
Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection [7–9]. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.
Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Full Name
chemokine (C-C motif) ligand 2
References
Vásquez-Loarte T, Trubnykova M, Guio H. Genetic association meta-analysis: a new classification to assess ethnicity using the association of MCP-1 -2518 polymorphism and tuberculosis susceptibility as a model. BMC Genetics. 2015;16:128.
