( We provide with CD74 qPCR primers for gene expression analysis, MP200713 )
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|小鼠 CD74 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签||MG50738-ACG|
|小鼠 CD74 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签||MG50738-ACR|
|小鼠 CD74 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||MG50738-CF|
|小鼠 CD74 基因ORF全长cDNA克隆(表达载体), C-His 标签||MG50738-CH|
|小鼠 CD74 基因ORF全长cDNA克隆(表达载体), C-Myc 标签||MG50738-CM|
|小鼠 CD74 基因ORF全长cDNA克隆(表达载体), C-HA 标签||MG50738-CY|
|小鼠 CD74 基因ORF全长cDNA(克隆载体)||MG50738-G|
|小鼠 CD74 基因ORF全长cDNA克隆(表达载体), N-Flag 标签||MG50738-NF|
|小鼠 CD74 基因ORF全长cDNA克隆(表达载体), N-His 标签||MG50738-NH|
|小鼠 CD74 基因ORF全长cDNA克隆(表达载体), N-Myc 标签||MG50738-NM|
|小鼠 CD74 基因ORF全长cDNA克隆(表达载体), N-HA 标签||MG50738-NY|
|小鼠 CD74 基因ORF全长cDNA克隆(表达载体)||MG50738-UT|
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD74, also known as HLA class2 histocompatibility antigen gamma chain and HLA-DR antigens-associated invariant chain, is a polypeptide involved in the formation and transport of MHC class2 protein. CD74 is expressed by B cells, macrophages, and Reed-Sternberg cells. When MHC class 2 protein was in the rough ER, its peptide-binding cleft was blocked by CD74 to prevent it from interacting with the endogenous peptides. CD74 also serves to facilitate MHC class2's export from ER.