CES2 cDNA ORF Clone, Mouse, C-HA tag

Cat: MG50515-CY
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CES2 cDNA ORF Clone, Mouse, C-HA tag 基本信息
基因
种属
Mouse
NCBI 参考序列号
参考序列ORF长度
1686 bp
描述
Full length Clone DNA of Mouse carboxylesterase 2 with C terminal HA tag.
质粒
启动子
Enhanced CMV promoter
载体
pCMV3-C-HA
标签序列
HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

CES2 cDNA ORF Clone, Mouse, C-HA tag Alternative Names
ces2A3 cDNA ORF Clone, Mouse
CES2 Background Information

Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and beroin. It also serves to hydrolyze long-chain fatty acid esters and thioesters. It is speculated that carboxylesterases may play a role in lipid metabolism and the blood-brain barrier system and together with isform 1, are a serine esterase involved in both drug metabolism and activation. Human carboxylesterase 2 is commonly expressed in tumor tissues and irinotecan, a topoisomerase I inhibitor commonly used in the treatment of many solid tumors.

Full Name
carboxylesterase 2
References
  • Imai T. et al. (2006) Human carboxylesterase isozymes: catalytic properties and rational drug design. Drug metab pharmacokinet. 21 (3): 173-85.
  • Guang Xu, et al. (2002) Human carboxylesterase 2 is commonly expressed in tumor tissue and is correlated with activation of irinotecan. Clin Cancer Res. 8: 2605.
  • Zhang, et al. (2002) Comprehensive Evaluation of Carboxylesterase-2 Expression in Normal Human Tissues Using Tissue Array Analysis. Applied Immunohistochemistry & Molecular Morphology. 10 (4): 374-80.
  • CES2 cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    CES2 cDNA ORF Clone in Cloning Vector, Mouse MG50515-M
    CES2 cDNA ORF Clone, Mouse, untagged MG50515-UT
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    CES2 cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    CES2 cDNA ORF Clone in Cloning Vector, Human HG10380-M
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    CES2 cDNA ORF Clone, Human, N-GFPSpark® tag HG10380-ANG
    CES2 cDNA ORF Clone, Human, C-OFPSpark® tag HG10380-ACR
    CES2 cDNA ORF Clone, Human, N-OFPSpark® tag HG10380-ANR
    CES2 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10380-CF
    CES2 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10380-NF
    CES2 cDNA ORF Clone, Human, C-His tag HG10380-CH
    CES2 cDNA ORF Clone, Human, N-His tag HG10380-NH
    CES2 cDNA ORF Clone, Human, C-HA tag HG10380-CY
    CES2 cDNA ORF Clone, Human, N-HA tag HG10380-NY
    CES2 cDNA ORF Clone, Human, C-Myc tag HG10380-CM
    CES2 cDNA ORF Clone, Human, N-Myc tag HG10380-NM
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