Claudin-11 cDNA ORF Clone, Mouse, N-Myc tag

Cat: MG51441-NM

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Claudin-11 cDNA ORF Clone, Mouse, N-Myc tag 基本信息

基因

种属
Mouse
NCBI 参考序列号
参考序列ORF长度
624 bp
描述
Full length Clone DNA of Mouse claudin 11 with N terminal Myc tag.

质粒

启动子
Enhanced CMV promoter
载体
标签序列
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.

筛选

抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression

储存 & 运输

运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

Claudin-11 cDNA ORF Clone, Mouse, N-Myc tag Alternative Names

Claudin-11 cDNA ORF Clone, Mouse;Claudin11 cDNA ORF Clone, Mouse;Osp cDNA ORF Clone, Mouse;Otm cDNA ORF Clone, Mouse

Claudin-11 Background Information

Claudin-11, also known as CLDN11, belongs to the group of claudins. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands function as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.Claudin-11 is a tight junction associated protein and is a major component of central nervous system (CNS) myelin that is necessary for normal CNS function. Human blood-testis barrier disruption is related to a dysfunction of CLDN11 gene. It plays an important role in regulating proliferation and migration of oligodendrocytes.

Full Name
claudin 11
References
  • Tsukita S, et al. (2001) Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol. 2(4): 285-3.
  • Heiskala M, et al. (2001) The roles of claudin superfamily proteins in paracellular transport. Traffic 2. (2):93-8.
  • Bronstein JM, et al. (2000) Involvement of OSP/claudin-11 in oligodendrocyte membrane interactions: role in biology and disease. J Neurosci Res. 59(6):706-11.
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    Claudin-11 cDNA ORF Clone, Mouse, C-His tag MG51441-CH
    Claudin-11 cDNA ORF Clone, Mouse, N-His tag MG51441-NH
    Claudin-11 cDNA ORF Clone, Mouse, C-HA tag MG51441-CY
    Claudin-11 cDNA ORF Clone, Mouse, N-HA tag MG51441-NY
    Claudin-11 cDNA ORF Clone, Mouse, C-Myc tag MG51441-CM
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