ESM1 qPCR Primer Pairs, Mouse

Cat: MP201060
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ESM1 qPCR Primer Pairs, Mouse 基本信息
Target Details
种属:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
应用:
SYBR® Green-based quantitative real-time PCR (qPCR).
质控:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
储存 & 运输
运输:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
储存:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
ESM1 qPCR Primer Pairs, Mouse Alternative Names
0610042H23Rik qPCR Primer Pairs, Mouse;AV004503 qPCR Primer Pairs, Mouse;ESM-1 qPCR Primer Pairs, Mouse
ESM1 Background Information

ESM1 is a secreted protein which is produced by adipocytes. It has been noticed that ESM1 may play some role in obesity-associated vascular disease since circulating ESM-1 levels are reduced in the overweight and obese. ESM1 is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of ESM1 gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. Recently, ESM1 has been described as a specific biomarker of tip cells during neoangiogenesis. Its expression has been shown to be increase in presence of pro-angiogenic growth factors such as VEGF or FGF-2. In hypervascularized cancers, overexpression of endocan has been detected by immunohistochemistry using monoclonal antibodies against ESM1.

Full Name
endothelial cell-specific molecule 1
References
  • Cong R, et al. (2006) Hhex is a direct repressor of endothelial cell-specific molecule 1 (ESM-1). Biochem. Biophys Res Commun. 346(2):535-45.
  • Aitkenhead M, et al. (2002) Identification of endothelial cell genes expressed in an in vitro model of angiogenesis: induction of ESM-1, (beta)ig-h3, and NrCAM. Microvasc Res. 63(2): 159-71.
  • Lassalle P, et al. (1996) ESM-1 is a novel human endothelial cell-specific molecule expressed in lung and regulated by cytokines. J Biol Chem. 271(34):20458-64.
  • ESM1 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    ESM1 cDNA ORF Clone in Cloning Vector, Mouse MG51108-G
    ESM1 cDNA ORF Clone, Mouse, untagged MG51108-UT
    ESM1 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51108-ACG
    ESM1 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51108-ACGLN
    ESM1 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG51108-ACR
    ESM1 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG51108-CF
    ESM1 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG51108-NF
    ESM1 cDNA ORF Clone, Mouse, C-His tag MG51108-CH
    ESM1 cDNA ORF Clone, Mouse, N-His tag MG51108-NH
    ESM1 cDNA ORF Clone, Mouse, C-HA tag MG51108-CY
    ESM1 cDNA ORF Clone, Mouse, N-HA tag MG51108-NY
    ESM1 cDNA ORF Clone, Mouse, C-Myc tag MG51108-CM
    ESM1 cDNA ORF Clone, Mouse, N-Myc tag MG51108-NM

    ESM1 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    ESM1 cDNA ORF Clone in Cloning Vector, Human HG11578-M
    ESM1 cDNA ORF Clone, Human, untagged HG11578-UT
    ESM1 cDNA ORF Clone, Human, C-GFPSpark® tag HG11578-ACG
    ESM1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG11578-ACGLN
    ESM1 cDNA ORF Clone, Human, C-OFPSpark® tag HG11578-ACR
    ESM1 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG11578-CF
    ESM1 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG11578-NF
    ESM1 cDNA ORF Clone, Human, C-His tag HG11578-CH
    ESM1 cDNA ORF Clone, Human, N-His tag HG11578-NH
    ESM1 cDNA ORF Clone, Human, C-HA tag HG11578-CY
    ESM1 cDNA ORF Clone, Human, N-HA tag HG11578-NY
    ESM1 cDNA ORF Clone, Human, C-Myc tag HG11578-CM
    ESM1 cDNA ORF Clone, Human, N-Myc tag HG11578-NM
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