MST4 qPCR Primer Pairs, Mouse

Cat: MP201046
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MST4 qPCR Primer Pairs, Mouse 基本信息
Target Details
种属:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
应用:
SYBR® Green-based quantitative real-time PCR (qPCR).
质控:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
储存 & 运输
运输:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
储存:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
MST4 qPCR Primer Pairs, Mouse Alternative Names
2610018G03Rik qPCR Primer Pairs, Mouse;Mst4 qPCR Primer Pairs, Mouse
MST4 Background Information

MST4, also known as mammalian STE20-like protein kinase 4, is a novel member of the germinal center kinase subfamily of human Ste20-like kinases and is closely related to MST3. The 416 amino acid full-length MST4 contains a C-terminal regulatory domain and an N-terminal kinase domain, both of which are required for full activation of the kinase. MST4 is highly expressed in placenta, thymus, and peripheral blood leukocytes. MST4 specifically activates ERK but not JNK or p38 MAPK in transient transfected cells or in stable cell lines, and thus is biologically active in the activation of MEK/ERK pathway mediating cell growth and transformation. Further, MST4 kinase activity is stimulated significantly by epidermal growth factor receptor (EGFR) ligands, which are known to promote growth of certain cancer cells. Accordingly, MST4 have a potential role in signal transduction pathways involved in cancer progression. Three alternatively spliced isoform of MST4 have been isolated, and isoform 3 lacks an exon encoding kinase domain and may function as a dominant-negative regulator of the MST4 kinase.

Full Name
serine/threonine protein kinase 26
References

1. Qian, Z. et al., 2001, J Biol Chem. 276 :22439-45.

2. Lin, JL. et al., 2001, Oncogene. 20: 6559-6569.

3. Sung V, et al., 2003, Cancer research. 63: 3356-63.

4. Ma, X. et al., 2007, Molecular biology of the cell. 18:1965-78.

5. ten Klooster JP, et al., 2009, Developmental cell. 16:551-62.

MST4 qPCR Primer Pairs, Mouse, Related Products

Product Name Catalog#(PDF)
MST4 cDNA ORF Clone in Cloning Vector, Mouse MG51088-G
MST4 cDNA ORF Clone, Mouse, untagged MG51088-UT
MST4 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51088-ACG
MST4 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51088-ACGLN
MST4 cDNA ORF Clone, Mouse, N-GFPSpark® tag MG51088-ANG
MST4 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG51088-ACR
MST4 cDNA ORF Clone, Mouse, N-OFPSpark® tag MG51088-ANR
MST4 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG51088-CF
MST4 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG51088-NF
MST4 cDNA ORF Clone, Mouse, C-His tag MG51088-CH
MST4 cDNA ORF Clone, Mouse, N-His tag MG51088-NH
MST4 cDNA ORF Clone, Mouse, C-HA tag MG51088-CY
MST4 cDNA ORF Clone, Mouse, N-HA tag MG51088-NY
MST4 cDNA ORF Clone, Mouse, C-Myc tag MG51088-CM
MST4 cDNA ORF Clone, Mouse, N-Myc tag MG51088-NM

MST4 qPCR Primer Pairs, Human, Related Products

Product Name Catalog#(PDF)
MST4 cDNA ORF Clone in Cloning Vector, Human HG10667-M
MST4 cDNA ORF Clone, Human, untagged HG10667-UT
MST4 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10667-ACGLN
MST4 cDNA ORF Clone, Human, C-GFPSpark® tag HG10667-ACG
MST4 cDNA ORF Clone, Human, N-GFPSpark® tag HG10667-ANG
MST4 cDNA ORF Clone, Human, C-OFPSpark® tag HG10667-ACR
MST4 cDNA ORF Clone, Human, N-OFPSpark® tag HG10667-ANR
MST4 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10667-CF
MST4 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10667-NF
MST4 cDNA ORF Clone, Human, C-His tag HG10667-CH
MST4 cDNA ORF Clone, Human, N-His tag HG10667-NH
MST4 cDNA ORF Clone, Human, C-HA tag HG10667-CY
MST4 cDNA ORF Clone, Human, N-HA tag HG10667-NY
MST4 cDNA ORF Clone, Human, C-Myc tag HG10667-CM
MST4 cDNA ORF Clone, Human, N-Myc tag HG10667-NM
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