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小鼠 NCF2 / NCF-2 / P67phox 基因ORF全长cDNA克隆(表达载体)

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Mouse NCF2 cDNA Clone产品信息
NCBI注册码:NM_010877.4
参考序列ORF长度:1578bp
cDNA基因描述:Full length Clone DNA of Mus musculus neutrophil cytosolic factor 2.
分子别称:NOXA2, Ncf-2, p67phox
分子种属:Mouse
载体:pCMV3-untagged
质粒:
限制性酶切位点:
Tag序列:
序列信息:
测序引物:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
启动子:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
抗生素(大肠杆菌):Ampicilin
抗生素(哺乳动物细胞):Hygromycin
运输方式:Each tube contains lyophilized plasmid.
储存方法:The lyophilized plasmid can be stored at room temperature for three months.
小鼠 NCF2 / NCF-2 / P67phox 基因ORF全长cDNA克隆(表达载体) on other vectors
Product nameProduct name
研究背景

NCF2, also known as NCF-2 and p67phox, is a subunit of the multi-protein NADPH oxidase complex. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.

参考资料
  • Wientjes FB. et al., 1996, Semin Cell Biol. 6 (6): 357-65.
  • DeLeo FR. et al., 1997, J Leukoc Biol. 60 (6): 677-91.
  • Dorseuil O. et al., 1997, C R Seances Soc Biol Fil. 191 (2): 237-46.
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    货号: MG52449-UT
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