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小鼠 NCF2 / NCF-2 / P67phox 基因ORF全长cDNA克隆(表达载体)

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    小鼠 NCF2 cDNA Clone产品信息
    NCBI注册码:NM_010877.4
    参考序列ORF长度:1578bp
    cDNA基因描述:Full length Clone DNA of Mus musculus neutrophil cytosolic factor 2.
    分子别称:NOXA2, Ncf-2, p67phox
    分子种属:Mouse
    载体:pCMV3-untagged
    质粒:
    限制性酶切位点:
    Tag序列:
    序列信息:
    测序引物:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
    ( We provide with NCF2 qPCR primers for gene expression analysis, MP202322 )
    启动子:Enhanced CMV mammalian cell promoter
    Application:Stable or Transient mammalian expression
    抗生素(大肠杆菌):Ampicillin
    抗生素(哺乳动物细胞):Hygromycin
    运输方式:Each tube contains lyophilized plasmid.
    储存方法:The lyophilized plasmid can be stored at room temperature for three months.
    小鼠 NCF2 / NCF-2 / P67phox 基因ORF全长cDNA克隆(表达载体) on other vectors
    Product nameProduct name
    研究背景

    NCF2, also known as NCF-2 and p67phox, is a subunit of the multi-protein NADPH oxidase complex. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.

    参考资料
  • Wientjes FB. et al., 1996, Semin Cell Biol. 6 (6): 357-65.
  • DeLeo FR. et al., 1997, J Leukoc Biol. 60 (6): 677-91.
  • Dorseuil O. et al., 1997, C R Seances Soc Biol Fil. 191 (2): 237-46.
  • Size / Price
    货号: MG52449-UT
    目录价: 
    单价:      (You Save: )

    Datasheet & Documentation

    产品数据可能随批次变化,最新数据请详见随货说明书。
    请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”