( We provide with PROCR qPCR primers for gene expression analysis, MP200845 )
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|小鼠 Epcr/PROCR 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签||MG50874-ACG|
|小鼠 Epcr/PROCR 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签||MG50874-ACR|
|小鼠 Epcr/PROCR 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||MG50874-CF|
|小鼠 Epcr/PROCR 基因ORF全长cDNA克隆(表达载体), C-His 标签||MG50874-CH|
|小鼠 Epcr/PROCR 基因ORF全长cDNA克隆(表达载体), C-Myc 标签||MG50874-CM|
|小鼠 Epcr/PROCR 基因ORF全长cDNA克隆(表达载体), C-HA 标签||MG50874-CY|
|小鼠 Epcr/PROCR 基因ORF全长cDNA(克隆载体)||MG50874-G|
|小鼠 Epcr/PROCR 基因ORF全长cDNA克隆(表达载体), N-Flag 标签||MG50874-NF|
|小鼠 Epcr/PROCR 基因ORF全长cDNA克隆(表达载体), N-His 标签||MG50874-NH|
|小鼠 Epcr/PROCR 基因ORF全长cDNA克隆(表达载体), N-Myc 标签||MG50874-NM|
|小鼠 Epcr/PROCR 基因ORF全长cDNA克隆(表达载体), N-HA 标签||MG50874-NY|
|小鼠 Epcr/PROCR 基因ORF全长cDNA克隆(表达载体)||MG50874-UT|
Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels), activated protein C is found maily near endothelial cells. Protein C is pleiotropic, with two main functions: anticoagulation and cytoprotection. Which function will be performed depend on whether or not protein C remains bind to EPCR after activated. The anticoagulation occurs when it does not. In this case, protein C functions as an anticoagulant by irreversibly proteolytically inactivating Factor Va and Factor VIIIa, turning them into Factor Vi and Factor VIIIi respectively. When still bound to EPCR, activated protein C performs its cytoprotective effects, acting on the effector substrate PAR-1, protease-activated receptor-1. To a degree, APC's anticoagulant properties are independent of its cytoprotective ones, in that expression of one pathway is not affected by the existence of the other.