Transferrin Receptor cDNA ORF Clone, Mouse, C-DDK (Flag®) tag

Cat: MG50741-CF

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Transferrin Receptor cDNA ORF Clone, Mouse, C-DDK (Flag®) tag 基本信息

基因

种属
Mouse
NCBI 参考序列号
参考序列ORF长度
2331 bp
序列描述
Identical with the Gene Bank Ref. ID sequence.
描述
Full length Clone DNA of Mouse transferrin receptor with C terminal Flag tag.

质粒

启动子
Enhanced CMV promoter
载体
限制性酶切位点
KpnI + NotI(6kb+2.33kb)
标签序列
FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.

筛选

抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression

储存 & 运输

运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

Transferrin Receptor cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

Transferrin Receptor cDNA ORF Clone, Mouse, C-DDK (Flag®) tag Validated Images

Cynomolgus CDCP1 Gene Plasmid Map 5627

Transferrin Receptor cDNA ORF Clone, Mouse, C-DDK (Flag®) tag Alternative Names

2610028K12Rik cDNA ORF Clone, Mouse;AI195355 cDNA ORF Clone, Mouse;AI426448 cDNA ORF Clone, Mouse;AU015758 cDNA ORF Clone, Mouse;CD71 cDNA ORF Clone, Mouse;E430033M20Rik cDNA ORF Clone, Mouse;Mtvr-1 cDNA ORF Clone, Mouse;Mtvr1 cDNA ORF Clone, Mouse;p90 cDNA ORF Clone, Mouse;TFR cDNA ORF Clone, Mouse;TFR1 cDNA ORF Clone, Mouse;TR cDNA ORF Clone, Mouse;Trfr cDNA ORF Clone, Mouse

Transferrin Receptor Background Information

Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p90, CD71 and TFRC, is a single-pass type II membrane protein which belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.

Full Name
transferrin receptor
References
  • Douabin-Gicquel V., et al., 2001,Hum. Genet. 109:393-401.
  • Ryschich,E. et al., 2004,Eur J Cancer. 40 (9):1418-22.
  • Tosoni D., et al., 2005, Cell 123:875-888.
  • Wollscheid B., et al., 2009, Nat. Biotechnol. 27:378-386.
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