TGFBR3 cDNA ORF Clone, Mouse, N-Myc tag

Cat: MG50542-NM

Contact us:

215-583-7898
order@sinobiological.com
Distributors

All TGFBR3 Reagents

CRO Services

Product recommended


All TGFBR3 Reagents

TGFBR3 cDNA ORF Clone, Mouse, N-Myc tag 基本信息

基因

种属
Mouse
NCBI 参考序列号
参考序列ORF长度
2553 bp
描述
Full length Clone DNA of Mouse transforming growth factor, beta receptor III with N terminal Myc tag.

质粒

启动子
Enhanced CMV promoter
标签序列
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.

筛选

抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression

储存 & 运输

运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

TGFBR3 cDNA ORF Clone, Mouse, N-Myc tag Alternative Names

1110036H20Rik cDNA ORF Clone, Mouse;AU015626 cDNA ORF Clone, Mouse;AW215636 cDNA ORF Clone, Mouse;TBRIII cDNA ORF Clone, Mouse

TGFBR3 Background Information

Betaglycan also known as transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan. TGFBR3 is a transforming growth factor (TGF)-beta type III receptor. This receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is the TGF-β component most commonly downregulated among localized human prostate cancer studies. TGFBR3 knockdown led to focus formation and enhanced expression of CD133, a marker found on prostate cancer stem cells. TGFBR3 is an accessory receptor that binds to and modulates the activities of both transforming growth factor-beta (TGFβ) and inhibin, two members of the TGFβ superfamily of growth factors that regulate many aspects of reproductive biology. TGFBR3 is known to be expressed in adult testis and ovary, but little is known about this receptor during gonadogenesis.

Full Name
transforming growth factor, beta receptor III
References
  • Johnson DW, et al. (1996) Assignment of human transforming growth factor-beta type I and type III receptor genes (TGFBR1 and TGFBR3) to 9q33-q34 and 1p32-p33, respectively. Genomics. 28 (2): 356-7.
  • Rotzer D, et al. (2001) Type III TGF-beta receptor-independent signalling of TGF-beta2 via T betaRII-B, an alternatively spliced TGF- type II receptor. EMBO J. 20 (3): 480-90.
  • Gao J, et al. (1999) Expression of transforming growth factor-beta receptors types II and III within various cells in the rat periodontium. J Periodont Res. 34 (2): 113-22.
  • TGFBR3 cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    TGFBR3 cDNA ORF Clone in Cloning Vector, Mouse MG50542-M
    TGFBR3 cDNA ORF Clone, Mouse, untagged MG50542-UT
    TGFBR3 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50542-ACG
    TGFBR3 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50542-ACGLN
    TGFBR3 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50542-ACR
    TGFBR3 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50542-CF
    TGFBR3 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50542-NF
    TGFBR3 cDNA ORF Clone, Mouse, C-His tag MG50542-CH
    TGFBR3 cDNA ORF Clone, Mouse, N-His tag MG50542-NH
    TGFBR3 cDNA ORF Clone, Mouse, C-HA tag MG50542-CY
    TGFBR3 cDNA ORF Clone, Mouse, N-HA tag MG50542-NY
    TGFBR3 cDNA ORF Clone, Mouse, C-Myc tag MG50542-CM
    TGFBR3 qPCR Primer Pairs, Mouse MP200534

    TGFBR3 cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    TGFBR3 cDNA ORF Clone in Cloning Vector, Human HG10778-M
    TGFBR3 cDNA ORF Clone, Human, untagged HG10778-UT
    TGFBR3 cDNA ORF Clone, Human, C-GFPSpark® tag HG10778-ACG
    TGFBR3 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10778-ACGLN
    TGFBR3 cDNA ORF Clone, Human, C-OFPSpark® tag HG10778-ACR
    TGFBR3 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10778-CF
    TGFBR3 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10778-NF
    TGFBR3 cDNA ORF Clone, Human, C-His tag HG10778-CH
    TGFBR3 cDNA ORF Clone, Human, N-His tag HG10778-NH
    TGFBR3 cDNA ORF Clone, Human, C-HA tag HG10778-CY
    TGFBR3 cDNA ORF Clone, Human, N-HA tag HG10778-NY
    TGFBR3 cDNA ORF Clone, Human, C-Myc tag HG10778-CM
    TGFBR3 cDNA ORF Clone, Human, N-Myc tag HG10778-NM
    TGFBR3 qPCR Primer Pairs, Human HP100906
    info info
    添加购物车成功! 添加购物车失败!