TIM-1 / KIM-1 Matched ELISA Antibody Pair Set,Mouse

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TIM-1 / KIM-1 Matched ELISA Antibody Pair Set,Mouse 产品信息

产品名称
TIM-1 / KIM-1 Matched ELISA Antibody Pair Set,Mouse
检测原理
Solid Phase Sandwich ELISA
特异性
Quantitative determination of Mouse TIM-1 / KIM-1
线性范围
18.75-1200 pg/mL
ELISA 抗体对套装(非即用型)组分
1. Capture Antibody 0.5 mg/mL of rabbit anti-Mouse TIM-1 / KIM-1 / HACVR monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 2 μg/mL in PBS before coating. (Catalog: # 50321-R152)
2. Detection Antibody 0.2 mg/mL of rabbit anti-Mouse TIM-1 / KIM-1 / HACVR polyclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.25 μg/mL in detection antibody dilution buffer before use.
3. Standard Each vial contains 38 ng of recombinant Mouse TIM-1 / KIM-1 / HACVR. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 1200 pg/mL is recommended.
产品概述
This TIM-1 / KIM-1 Matched ELISA Antibody Pair Set,Mouse is a solid phase sandwich ELISA for quantitative determination of Mouse TIM-1 / KIM-1 . It contains Mouse TIM-1 / KIM-1 capture antibody, Mouse TIM-1 / KIM-1 detector antibody (HRP) and a highly purified HEK293-expressed recombinant Mouse TIM-1 / KIM-1 protein. This Pair Set is at affordable price for researchers.
运输方式
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
储存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

TIM-1 / KIM-1 Matched ELISA Antibody Pair Set,Mouse 图片

TIM-1 / KIM-1 Matched ELISA Antibody Pair Set,Mouse: 别称

AI503787 Matched ELISA Antibody Pair Set, Mouse; KIM-1 Matched ELISA Antibody Pair Set, Mouse; TIM-1 Matched ELISA Antibody Pair Set, Mouse; Tim1 Matched ELISA Antibody Pair Set, Mouse; Timd1 Matched ELISA Antibody Pair Set, Mouse

TIM-1 / KIM-1 背景信息

HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â… integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
全称
hepatitis A virus cellular receptor 1
参考文献
  • Tami C, et al. (2007) Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions. J Virol. 81(7): 3437-46.
  • Rees AJ, et al. (2008) Kim-1/Tim-1: from biomarker to therapeutic target? Nephrol Dial Transplant. 23(11): 3394-6.
  • Chaturvedi S, et al. (2009) Assay validation for KIM-1: human urinary renal dysfunction biomarker. Int J Biol Sci. 5(2): 128-34.
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