TNFRSF1A cDNA ORF Clone, Mouse, C-HA tag

Cat: MG50496-CY
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TNFRSF1A cDNA ORF Clone, Mouse, C-HA tag 基本信息
基因
种属
Mouse
NCBI 参考序列号
参考序列ORF长度
1407 bp
序列描述
Identical with the Gene Bank Ref. ID sequence.
描述
Full length Clone DNA of Mouse tumor necrosis factor receptor superfamily, member 1a with C terminal HA tag.
质粒
启动子
Enhanced CMV promoter
载体
pCMV3-C-HA
限制性酶切位点
KpnI + XbaI(6kb+1.41kb)
标签序列
HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.
TNFRSF1A cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

TNFRSF1A cDNA ORF Clone, Mouse, C-HA tag Validated Images
other Green fluorescent protein / GFP Gene Plasmid Map 5612
TNFRSF1A cDNA ORF Clone, Mouse, C-HA tag Alternative Names
CD120a cDNA ORF Clone, Mouse;FPF cDNA ORF Clone, Mouse;p55 cDNA ORF Clone, Mouse;p55-R cDNA ORF Clone, Mouse;TNF-alphaR1 cDNA ORF Clone, Mouse;TNF-R cDNA ORF Clone, Mouse;TNF-R-I cDNA ORF Clone, Mouse;TNF-R1 cDNA ORF Clone, Mouse;TNF-R55 cDNA ORF Clone, Mouse;TNFalpha-R1 cDNA ORF Clone, Mouse;TNFAR cDNA ORF Clone, Mouse;Tnfr-2 cDNA ORF Clone, Mouse;Tnfr1 cDNA ORF Clone, Mouse;TNFR60 cDNA ORF Clone, Mouse;TNFRI cDNA ORF Clone, Mouse;TNFRp55 cDNA ORF Clone, Mouse
TNFRSF1A Background Information

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.

Full Name
tumor necrosis factor receptor superfamily member 1A
Research Areas
References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Cottin V, et al. (2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. The journal of immunology. 168: 4095-102.
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