NGF (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)

All NGF reagents are produced in house and quality controlled, including 18 NGF Antibody, 2 NGF ELISA, 51 NGF Gene, 3 NGF Lysate, 4 NGF Protein, 3 NGF qPCR. All NGF reagents are ready to use.

NGF Protein (4)

    NGF Antibody (18)

      NGF ELISA 试剂盒(即用型)& ELISA 抗体对套装(非即用型)(2)

      NGF cDNA Clone (51)

      NM_002506.2
      NM_001112698.1

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_001277055.1

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_001194950.1

      克隆载体 cDNA 产品

      In lentiviral vector

      NGF Lysate (3)

        NGF 分子背景

        Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. In addition, previous studies indicated that NGF may also have an important role in the regulation of the immune system.

        NGF 参考文献

        • Castellanos MR, et al. (2003) Evaluation of the neurorestorative effects of the murine beta-nerve growth factor infusions in old rat with cognitive deficit. Biochem Biophys Res Commun. 312(4): 867-72.
        • Wang TH, et al. (2008) Effects of pcDNA3-beta-NGF gene-modified BMSC on the rat model of Parkinson's disease. J Mol Neurosci. 35(2): 161-9.
        • Perrard MH, et al. (2009) Redundancy of the effect of TGFbeta1 and beta-NGF on the second meiotic division of rat spermatocytes. Microsc Res Tech. 72(8): 596-602.

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