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PROS1 / 蛋白 S 抗体, 兔多抗, 抗原亲和纯化

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 PROS1 抗体产品信息
免疫原:Recombinant Human PROS1 / Protein S protein (Catalog#12179-H08H)
克隆号:
Ig 类型:Rabbit IgG
浓度:
内毒素:
缓冲液:0.2 μm filtered solution in PBS
抗体制备方法:Produced in rabbits immunized with purified, recombinant Human PROS1 / Protein S (rh PROS1 / Protein S; Catalog#12179-H08H; P07225; Met1-Ser676). PROS1 / Protein S specific IgG was purified by Human PROS1 / Protein S affinity chromatography.
Other PROS1 抗体 Products
PROS1/Protein S 研究背景

PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.

 PROS1/Protein S 参考资料
  • Beauchamp NJ. et al., 2004, Br J Haematol. 125 (5): 647-54.
  • García de Frutos P. et al., 2007, Thromb Haemost. 98 (3): 543-56.
  • Rezende SM. et al., 2004, Blood. 103 (4): 1192-201.
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    货号: 12179-T16-200
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