Anti-Protein S Antibody

Cat: 12179-T16

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Anti-Protein S Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-Protein S Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human Protein S
Immunogen
Recombinant Human PROS1 / Protein S protein (Catalog#12179-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human PROS1 / Protein S (rh PROS1 / Protein S; Catalog#12179-H08H; P07225; Met1-Ser676). PROS1 / Protein S specific IgG was purified by Human PROS1 / Protein S affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Anti-Protein S Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Protein S Antibody Alternative Names

Anti-PROS Antibody;Anti-Protein S Antibody;Anti-PS21 Antibody;Anti-PS22 Antibody;Anti-PS23 Antibody;Anti-PS24 Antibody;Anti-PS25 Antibody;Anti-PSA Antibody;Anti-THPH5 Antibody;Anti-THPH6 Antibody

Protein S Background Information

PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.

Full Name
protein S (alpha)
References
  • Beauchamp NJ. et al., 2004, Br J Haematol. 125 (5): 647-54.
  • García de Frutos P. et al., 2007, Thromb Haemost. 98 (3): 543-56.
  • Rezende SM. et al., 2004, Blood. 103 (4): 1192-201.
  • Product Description Host Clonality Application Catalog# (PDF)
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