( We provide with ACVRL1 qPCR primers for gene expression analysis, RP300129 )
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A myc tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a myc-tag allows one to follow the protein with an antibody against the Myc epitope. Examples are cellular localization studies by immunofluorescence or detection by Western blotting.
The peptide sequence of the myc-tag is: N-EQKLISEEDL-C (1202 Da). It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the tag directly behind the signal peptide of a secretory protein, since it can interfere with translocation into the secretory pathway.
|大鼠 ALK-1/ACVRL1 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签||RG80132-ACG|
|大鼠 ALK-1/ACVRL1 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签||RG80132-ACR|
|大鼠 ALK-1/ACVRL1 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||RG80132-CF|
|大鼠 ALK-1/ACVRL1 基因ORF全长cDNA克隆(表达载体), C-His 标签||RG80132-CH|
|大鼠 ALK-1/ACVRL1 基因ORF全长cDNA克隆(表达载体), C-Myc 标签||RG80132-CM|
|大鼠 ALK-1/ACVRL1 基因ORF全长cDNA克隆(表达载体), C-HA 标签||RG80132-CY|
|大鼠 ALK-1/ACVRL1 基因ORF全长cDNA(克隆载体)||RG80132-G|
|大鼠 ALK-1/ACVRL1 基因ORF全长cDNA克隆(表达载体), N-Flag 标签||RG80132-NF|
|大鼠 ALK-1/ACVRL1 基因ORF全长cDNA克隆(表达载体), N-His 标签||RG80132-NH|
|大鼠 ALK-1/ACVRL1 基因ORF全长cDNA克隆(表达载体), N-Myc 标签||RG80132-NM|
|大鼠 ALK-1/ACVRL1 基因ORF全长cDNA克隆(表达载体), N-HA 标签||RG80132-NY|
|大鼠 ALK-1/ACVRL1 基因ORF全长cDNA克隆(表达载体)||RG80132-UT|
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. On ligand binding, a heteromeric receptor complex forms consisting of two type II and two type I transmembrane serine/threonine kinases. ACVRL1 protein is expressed in certain blood vessels of kidney, spleen, heart and intestine, serving as an important role during vascular development. Mutations in ACVRL1 gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2 and vascular disease.