|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|大鼠 ADAM17 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签||RG80350-ACG|
|大鼠 ADAM17 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签||RG80350-ACR|
|大鼠 ADAM17 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||RG80350-CF|
|大鼠 ADAM17 基因ORF全长cDNA克隆(表达载体), C-His 标签||RG80350-CH|
|大鼠 ADAM17 基因ORF全长cDNA克隆(表达载体), C-Myc 标签||RG80350-CM|
|大鼠 ADAM17 基因ORF全长cDNA克隆(表达载体), C-HA 标签||RG80350-CY|
|大鼠 ADAM17 基因ORF全长cDNA(克隆载体)||RG80350-G|
|大鼠 ADAM17 基因ORF全长cDNA克隆(表达载体), N-Flag 标签||RG80350-NF|
|大鼠 ADAM17 基因ORF全长cDNA克隆(表达载体), N-His 标签||RG80350-NH|
|大鼠 ADAM17 基因ORF全长cDNA克隆(表达载体), N-Myc 标签||RG80350-NM|
|大鼠 ADAM17 基因ORF全长cDNA克隆(表达载体), N-HA 标签||RG80350-NY|
|大鼠 ADAM17 基因ORF全长cDNA克隆(表达载体)||RG80350-UT|
ADAM17 is a member of the ADAM protein family of disintegrins and metalloproteases. ADAM17 is ubiquitously expressed in the human colon, with increased activity in the colonic mucosa of patients with ulcerative colitis, a main form of inflammatory bowel disease. The expression of ADAM17 may be inhibited by ethanol. It is involved in the processing of tumor necrosis factor alpha (TNF-α) at the surface of the cell, and from within the intracellular membranes of the trans-Golgi network. ADAM17 also plays a role in the release of a diverse variety of membrane-anchored cytokines, cell adhesion molecules, receptors, ligands, and enzymes. ADAM17 may play a prominent role in the Notch signaling pathway, during the proteolytic release of the Notch intracellular domain (from the Notch1 receptor) that occurs following ligand binding.