( We provide with CD59 qPCR primers for gene expression analysis, RP300275 )
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|大鼠 CD59 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签||RG80299-ACG|
|大鼠 CD59 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签||RG80299-ACR|
|大鼠 CD59 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||RG80299-CF|
|大鼠 CD59 基因ORF全长cDNA克隆(表达载体), C-His 标签||RG80299-CH|
|大鼠 CD59 基因ORF全长cDNA克隆(表达载体), C-Myc 标签||RG80299-CM|
|大鼠 CD59 基因ORF全长cDNA克隆(表达载体), C-HA 标签||RG80299-CY|
|大鼠 CD59 基因ORF全长cDNA(克隆载体)||RG80299-G|
|大鼠 CD59 基因ORF全长cDNA克隆(表达载体), N-Flag 标签||RG80299-NF|
|大鼠 CD59 基因ORF全长cDNA克隆(表达载体), N-His 标签||RG80299-NH|
|大鼠 CD59 基因ORF全长cDNA克隆(表达载体), N-Myc 标签||RG80299-NM|
|大鼠 CD59 基因ORF全长cDNA克隆(表达载体), N-HA 标签||RG80299-NY|
|大鼠 CD59 基因ORF全长cDNA克隆(表达载体)||RG80299-UT|
CD59 glycoprotein, also known as 20 kDa homologous restriction factor, HRF20, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membrane protein which contains one UPAR/Ly6 domain. CD59 is a small, highly glycosylated, GPI-linked protein, with a wide expression profile. The soluble form of CD59 from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Defects in CD59 are the cause of CD59 deficiency (CD59D).