|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|大鼠 CD96/TACTILE 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签||RG80338-ACG|
|大鼠 CD96/TACTILE 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签||RG80338-ACR|
|大鼠 CD96/TACTILE 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||RG80338-CF|
|大鼠 CD96/TACTILE 基因ORF全长cDNA克隆(表达载体), C-His 标签||RG80338-CH|
|大鼠 CD96/TACTILE 基因ORF全长cDNA克隆(表达载体), C-Myc 标签||RG80338-CM|
|大鼠 CD96/TACTILE 基因ORF全长cDNA克隆(表达载体), C-HA 标签||RG80338-CY|
|大鼠 CD96/TACTILE 基因ORF全长cDNA(克隆载体)||RG80338-G|
|大鼠 CD96/TACTILE 基因ORF全长cDNA克隆(表达载体), N-Flag 标签||RG80338-NF|
|大鼠 CD96/TACTILE 基因ORF全长cDNA克隆(表达载体), N-His 标签||RG80338-NH|
|大鼠 CD96/TACTILE 基因ORF全长cDNA克隆(表达载体), N-Myc 标签||RG80338-NM|
|大鼠 CD96/TACTILE 基因ORF全长cDNA克隆(表达载体), N-HA 标签||RG80338-NY|
|大鼠 CD96/TACTILE 基因ORF全长cDNA克隆(表达载体)||RG80338-UT|
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor (PVR), a nectins and nectin-like protein family member serve to mediate cell-cell adhesion, cell migration, with the presence of an additional receptor, CD96. CD96 promotes NK cell adhesion to target cells expressing PVR, stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells. The effect the cells with mutated CD96 protein lost adhesion and growth activities indicates that CD96 mutations may cause a form of the C syndrome by interfering with cell adhesion and growth.