|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|大鼠 Cadherin-12/CDH12 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签||RG80279-ACG|
|大鼠 Cadherin-12/CDH12 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签||RG80279-ACR|
|大鼠 Cadherin-12/CDH12 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||RG80279-CF|
|大鼠 Cadherin-12/CDH12 基因ORF全长cDNA克隆(表达载体), C-His 标签||RG80279-CH|
|大鼠 Cadherin-12/CDH12 基因ORF全长cDNA克隆(表达载体), C-Myc 标签||RG80279-CM|
|大鼠 Cadherin-12/CDH12 基因ORF全长cDNA克隆(表达载体), C-HA 标签||RG80279-CY|
|大鼠 Cadherin-12/CDH12 基因ORF全长cDNA(克隆载体)||RG80279-G|
|大鼠 Cadherin-12/CDH12 基因ORF全长cDNA克隆(表达载体), N-Flag 标签||RG80279-NF|
|大鼠 Cadherin-12/CDH12 基因ORF全长cDNA克隆(表达载体), N-His 标签||RG80279-NH|
|大鼠 Cadherin-12/CDH12 基因ORF全长cDNA克隆(表达载体), N-Myc 标签||RG80279-NM|
|大鼠 Cadherin-12/CDH12 基因ORF全长cDNA克隆(表达载体), N-HA 标签||RG80279-NY|
|大鼠 Cadherin-12/CDH12 基因ORF全长cDNA克隆(表达载体)||RG80279-UT|
Classic Cadherins represent a family of calcium-dependent homophilic cell-cell adhesion molecules. They confer strong adhesiveness to animal cells when they are anchored to the actin cytoskeleton via their cytoplasmic binding partners, catenins. The cadherin/catenin adhesion system plays key roles in the morphogenesis and function of the vertebrate and invertebrate nervous systems. Furthermore, this system is involved in synaptic plasticity. Recent studies on the role of individual cadherin subtypes at synapses indicate that individual cadherin subtypes play their own unique role to regulate synaptic activities. Type II (atypical) cadherins are defined based on their lack of an HAV cell adhesion recognition sequence specific to type I cadherins. It has been observed that cells containing a specific cadherin subtype tend to cluster together to the exclusion of other types, both in cell culture and during development. Cadherin-12 also known as CDH12, is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherin-12 appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.