|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive ,Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokarfyotic expression systems.
|大鼠 VE-Cadherin/CD144 基因ORF全长cDNA克隆(表达载体), C-GFPSpark 标签||RG80276-ACG|
|大鼠 VE-Cadherin/CD144 基因ORF全长cDNA克隆(表达载体), C-OFPSpark 标签||RG80276-ACR|
|大鼠 VE-Cadherin/CD144 基因ORF全长cDNA克隆(表达载体), C-Flag 标签||RG80276-CF|
|大鼠 VE-Cadherin/CD144 基因ORF全长cDNA克隆(表达载体), C-His 标签||RG80276-CH|
|大鼠 VE-Cadherin/CD144 基因ORF全长cDNA克隆(表达载体), C-Myc 标签||RG80276-CM|
|大鼠 VE-Cadherin/CD144 基因ORF全长cDNA克隆(表达载体), C-HA 标签||RG80276-CY|
|大鼠 VE-Cadherin/CD144 基因ORF全长cDNA(克隆载体)||RG80276-G|
|大鼠 VE-Cadherin/CD144 基因ORF全长cDNA克隆(表达载体), N-Flag 标签||RG80276-NF|
|大鼠 VE-Cadherin/CD144 基因ORF全长cDNA克隆(表达载体), N-His 标签||RG80276-NH|
|大鼠 VE-Cadherin/CD144 基因ORF全长cDNA克隆(表达载体), N-Myc 标签||RG80276-NM|
|大鼠 VE-Cadherin/CD144 基因ORF全长cDNA克隆(表达载体), N-HA 标签||RG80276-NY|
|大鼠 VE-Cadherin/CD144 基因ORF全长cDNA克隆(表达载体)||RG80276-UT|
Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. VE-Cadherin is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. This specificity of VE-cadherin for vascular endothelial cells is important not only in blood and lymph vessel biology and medicine, but also for cell-type-based diagnoses, notably those of metastatic tumors. As a classical cadherin, VE-Cadherin links endothelial cells together by homophilic interactions mediated by its extracellular part and associates intracellularly with the actin cytoskeleton via catenins. Mechanisms that regulate VE-cadherin-mediated adhesion are important for the control of vascular permeability and leukocyte extravasation. In addition to its adhesive functions, VE-Cadherin regulates various cellular processes such as cell proliferation and apoptosis and modulates vascular endothelial growth factor receptor functions. Consequently, VE-cadherin is essential during embryonic angiogenesis.