Decorin qPCR Primer Pairs, Rat

Cat: RP300620
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Decorin qPCR Primer Pairs, Rat 基本信息
Target Details
种属:
Rat
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
应用:
SYBR® Green-based quantitative real-time PCR (qPCR).
质控:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
储存 & 运输
运输:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
储存:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
Decorin Background Information

Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core protein and a covalently linked glycosaminoglycan chain which is either chondroitin sulfate (CS) or dermatan sulfate (DS). As a component of connective tissue, decorin interacts with several extracellular matrix components, such as type I collagen and fibronectin, and plays a role in matrix assembly. Decorin resides in the tumor microenvironment and affects the biology of various types of cancer by downregulating the activity of several receptors involved in cell growth and survival. Decorin binds to and modulates the signaling of the epidermal growth factor receptor and other members of the ErbB family of receptor tyrosine kinases. It exerts its antitumor activity by a dual mechanism: via inhibition of these key receptors through their physical downregulation coupled with attenuation of their signaling, and by binding to and sequestering TGFbeta. Decorin also modulates the insulin-like growth factor receptor and the low-density lipoprotein receptor-related protein 1, which indirectly affects the TGFbeta receptor pathway. Decorin plays significant roles in tissue development and assembly, as well as playing both direct and indirect signaling roles.

Full Name
decorin
References
  • Mogyorsi A, et al. (1999) What is the role of decorin in diabetic kidney disease? Nephrol Dial Transplant. 14(5): 1078-81.
  • Reed CC, et al. (2002) The role of decorin in collagen fibrillogenesis and skin homeostasis. Glycoconj J. 19(4-5): 249-55.
  • Goldoni S, et al. (2008) Tumor microenvironment: Modulation by decorin and related molecules harboring leucine-rich tandem motifs. Int J Cancer. 123(11): 2473-9.
  • Decorin qPCR Primer Pairs, Rat, Related Products

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    Decorin qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
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    Decorin cDNA ORF Clone, Mouse, N-His tag MG51501-NH
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    Decorin qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    Decorin cDNA ORF Clone in Cloning Vector, Human HG10189-M
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    Decorin cDNA ORF Clone, Human, C-GFPSpark® tag HG10189-ACG
    Decorin cDNA ORF Clone, Human, C-OFPSpark® tag HG10189-ACR
    Decorin cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10189-CF
    Decorin cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10189-NF
    Decorin cDNA ORF Clone, Human, C-His tag HG10189-CH
    Decorin cDNA ORF Clone, Human, N-His tag HG10189-NH
    Decorin cDNA ORF Clone, Human, C-HA tag HG10189-CY
    Decorin cDNA ORF Clone, Human, N-HA tag HG10189-NY
    Decorin cDNA ORF Clone, Human, C-Myc tag HG10189-CM
    Decorin cDNA ORF Clone, Human, N-Myc tag HG10189-NM
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