Pleiotrophin cDNA ORF Clone, Rat, C-DDK (Flag®) tag

Cat: RG81121-CF
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All Pleiotrophin Reagents
CRO Services
Product recommended

All Pleiotrophin Reagents
Pleiotrophin cDNA ORF Clone, Rat, C-DDK (Flag®) tag 基本信息
基因
种属
Rat
NCBI 参考序列号
参考序列ORF长度
507 bp
描述
Full length Clone DNA of Rat pleiotrophin with C terminal Flag tag.
质粒
启动子
Enhanced CMV promoter
载体
pCMV3-C-FLAG
标签序列
FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
抗生素(大肠杆菌)
Kanamycin
抗生素(哺乳动物细胞)
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输
Each tube contains lyophilized plasmid.
储存
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

Pleiotrophin Background Information

HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. While in the adult central nervous system, it is expressed in an activity-dependent manner in the hippocampus where it can suppress long term potentiation induction. HB-GAM has a low expression in other areas of the adult brain, but it can be induced by ischemic insults, or targeted neuronal damaged in the entorhinal cortex or in the substantia nigra pars compacta. It is structurally related to midkine and retinoic acid induced heparin-binding protein and has a high affinity for heparin. HB-GAM binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. It also functions as a secreted growth factor and induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells.

Full Name
pleiotrophin
References
  • Vanderwinden JM, et al. (1992) Cellular distribution of the new growth factor pleiotrophin (HB-GAM) mRNA in developing and adult rat tissues. Anat Embryol. 186(4):387-406.
  • Lauri SE, et al. (1996) Activity-induced enhancement of HB-GAM expression in rat hippocampal slices. Neuroreport. 7(10):1670-4.
  • Pavlov I, et al. (2002) Role of heparin-binding growth-associated molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice. Mol Cell Neurosci. 20(2):330-42.
  • Pleiotrophin cDNA ORF Clone, Rat, Related Products

    Product Name Catalog#(PDF)
    Pleiotrophin cDNA ORF Clone in Cloning Vector, Rat RG81121-U
    Pleiotrophin cDNA ORF Clone, Rat, untagged RG81121-UT
    Pleiotrophin cDNA ORF Clone, Rat, C-GFPSpark® tag RG81121-ACG
    Pleiotrophin Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG81121-ACGLN
    Pleiotrophin cDNA ORF Clone, Rat, C-OFPSpark® tag RG81121-ACR
    Pleiotrophin cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG81121-NF
    Pleiotrophin cDNA ORF Clone, Rat, C-His tag RG81121-CH
    Pleiotrophin cDNA ORF Clone, Rat, N-His tag RG81121-NH
    Pleiotrophin cDNA ORF Clone, Rat, C-HA tag RG81121-CY
    Pleiotrophin cDNA ORF Clone, Rat, N-HA tag RG81121-NY
    Pleiotrophin cDNA ORF Clone, Rat, C-Myc tag RG81121-CM
    Pleiotrophin cDNA ORF Clone, Rat, N-Myc tag RG81121-NM
    Pleiotrophin qPCR Primer Pairs, Rat RP301078

    Pleiotrophin cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    Pleiotrophin cDNA ORF Clone in Cloning Vector, Mouse MG51000-G
    Pleiotrophin cDNA ORF Clone, Mouse, untagged MG51000-UT
    Pleiotrophin Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51000-ACGLN
    Pleiotrophin cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51000-ACG
    Pleiotrophin cDNA ORF Clone, Mouse, C-OFPSpark® tag MG51000-ACR
    Pleiotrophin cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG51000-CF
    Pleiotrophin cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG51000-NF
    Pleiotrophin cDNA ORF Clone, Mouse, C-His tag MG51000-CH
    Pleiotrophin cDNA ORF Clone, Mouse, N-His tag MG51000-NH
    Pleiotrophin cDNA ORF Clone, Mouse, C-HA tag MG51000-CY
    Pleiotrophin cDNA ORF Clone, Mouse, N-HA tag MG51000-NY
    Pleiotrophin cDNA ORF Clone, Mouse, C-Myc tag MG51000-CM
    Pleiotrophin cDNA ORF Clone, Mouse, N-Myc tag MG51000-NM
    Pleiotrophin qPCR Primer Pairs, Mouse MP200965

    Pleiotrophin cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    Pleiotrophin cDNA ORF Clone in Cloning Vector, Human HG10288-M
    Pleiotrophin cDNA ORF Clone, Human, untagged HG10288-UT
    Pleiotrophin Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10288-ACGLN
    Pleiotrophin cDNA ORF Clone, Human, C-GFPSpark® tag HG10288-ACG
    Pleiotrophin cDNA ORF Clone, Human, C-OFPSpark® tag HG10288-ACR
    Pleiotrophin cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10288-CF
    Pleiotrophin cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10288-NF
    Pleiotrophin cDNA ORF Clone, Human, C-His tag HG10288-CH
    Pleiotrophin cDNA ORF Clone, Human, N-His tag HG10288-NH
    Pleiotrophin cDNA ORF Clone, Human, C-HA tag HG10288-CY
    Pleiotrophin cDNA ORF Clone, Human, N-HA tag HG10288-NY
    Pleiotrophin cDNA ORF Clone, Human, C-Myc tag HG10288-CM
    Pleiotrophin cDNA ORF Clone, Human, N-Myc tag HG10288-NM
    Pleiotrophin qPCR Primer Pairs, Human HP100333
    info info
    添加购物车成功! 添加购物车失败!