Anti-ST6GAL1 Antibody (Rabbit Monoclonal antibody) General Information
Reacts with: Human
Recombinant Human ST6GAL1 / ST6GAL-I protein (Catalog#11590-H07H)
This antibody was obtained from a rabbit immunized with purified, recombinant Human ST6GAL1 / ST6GAL-I (rh ST6GAL1 / ST6GAL-I; Catalog#11590-H07H; P15907; Lys27-Cys406).
Monoclonal Rabbit IgG Clone #036
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-ST6GAL1 Antibody (Rabbit Monoclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-ST6GAL1 Antibody (Rabbit Monoclonal antibody) Images
Immunochemical staining of human ST6GAL1 in human prostate with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to epithelium.
Immunochemical staining of human ST6GAL1 in human kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Anti-ST6GAL1 Antibody Alternative Names
Anti-SIAT1 Antibody;Anti-ST6GalI Antibody;Anti-ST6N Antibody
ST6GAL1 Background Information
Beta-galactoside alpha-2,6-sialyltransferase 1, also known as B-cell antigen CD75, Sialyltransferase 1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6GAL1 and SIAT1, is a single-pass type II membrane protein which belongs to the glycosyltransferase 29 family. Sialyltransferases are key enzymes in the biosynthesis of sialoglycoconjugates that catalyze the transfer of sialic residue from its activated form to an oligosaccharidic acceptor. ST6GAL1 / SIAT1 is normally found in the?Golgi?but which can be proteolytically processed to a soluble form. It is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. β-Galactoside α2,6-sialyltransferases ST6GAL1 and ST6GAL2 are the two unique members of the ST6GAL family described in higher vertebrates. ST6GAL1 / SIAT1 transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
Collins,B.E. et al., 2006, Nat Immunol. 7(2):199-206. Videira,P.A. et al., 2008, Glycoconj J. 25(3): 259-68. Petit,D. et al., 2010, J Biol Chem. 285(49): 38399-414. Kroes,R.A. et al., 2010, Proc Natl Acad Sci USA.107(28):12646-51.