快速订购

Text Size:AAA

Trypsin-3 / PRSS3 抗体, 兔单抗

    产品数据评论相关产品实验方法
     PRSS3 抗体产品信息
    免疫原:Recombinant Human Trypsin-3 / PRSS3 protein (Catalog#11866-H08H)
    克隆号:001
    Ig 类型:Rabbit IgG
    浓度:
    内毒素:
    缓冲液:0.2 μm filtered solution in PBS with 5% trehalose
    抗体制备方法:This antibody was obtained from a rabbit immunized with purified, recombinant Human Trypsin-3 / PRSS3 (rh Trypsin-3 / PRSS3; Catalog#11866-H08H; P35030-3; Met1-Ser247).
    Other PRSS3 抗体 Products
    Trypsin-3/PRSS3 研究背景

    Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein which belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their inhibitors seems to be important for the development of CP. The trypsin inhibitor-degrading activity qualified PRSS3 as a candidate for a novel CP susceptibility gene. Trypsin-3 / PRSS3 has been implicated as a putative tumor suppressor gene due to its loss of expression, which is correlated with promoter hypermethylation, in esophageal squamous cell carcinoma and gastric adenocarcinoma.

     Trypsin-3/PRSS3 参考资料
  • Venter JC. et al., 2001, Science 291:1304-51.
  • Marsit,CJ. et al., 2005, Mol Carcinog 44 (2):146-50.
  • Rowen, L. et al., 2005, Mol Biol Evol. 22 (8):1712-20.
  • Rosendahl, J. et al., 2010, Pancreatology. 10 (2-3):243-9
  • Product nameProduct name
    Size / Price
    货号: 11866-R001-50
    目录价: 
    单价:      (You Save: )

    Datasheet & Documentation

    产品数据可能随批次变化,最新数据请详见随货说明书。
    请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”