FLT4 (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)

All FLT4 reagents are produced in house and quality controlled, including 10 FLT4 Antibody, 2 FLT4 ELISA, 29 FLT4 Gene, 4 FLT4 Lysate, 4 FLT4 Protein, 2 FLT4 qPCR. All FLT4 reagents are ready to use.

FLT4 Protein (4)

FLT4 Antibody (10)

FLT4 ELISA 试剂盒(即用型)& ELISA 抗体对套装(非即用型)(2)

FLT4 cDNA Clone (29)

NM_002020.4

克隆载体 cDNA 产品

In lentiviral vector

NM_182925.4

In expression vector

In lentiviral vector

NM_008029.2

克隆载体 cDNA 产品

In lentiviral vector

FLT4 Lysate (4)

更多受客户欢迎的产品

FLT4 分子背景

Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on.

FLT4 参考文献

  • Shushanov S, et al. (2000)VEGFc and VEGFR3 expression in human thyroid pathologies. Int J Cancer.86(1): 47-52.
  • Iljin K, et al. (2001) VEGFR3 gene structure, regulatory region, and sequence polymorphisms. FASEB J. 15(6): 1028-36.
  • Liu XE, et al. (2004) Expression and significance of VEGF-C and FLT-4 in gastric cancer. World J Gastroenterol. 10(3): 352-5.
  • Stearns ME, et al. (2004) Expression of a flt-4 (VEGFR3) splicing variant in primary human prostate tumors. VEGF D and flt-4t(Delta773-1081) overexpression is diagnostic for sentinel lymph node metastasis. Lab Invest. 84(6): 785-95.