All Vitronectin reagents are produced in house and quality controlled, including 8 Vitronectin Antibody, 2 Vitronectin ELISA, 39 Vitronectin Gene, 2 Vitronectin Lysate, 2 Vitronectin Protein, 3 Vitronectin qPCR. All Vitronectin reagents are ready to use.
Recombinant Vitronectin proteins are expressed by HEK293 Cells with fusion tags as C-His, N-His.
Vitronectinantibodies are validated with different applications, which are ELISA, ELISA(Det), WB, IHC-P, ELISA(Cap).
VitronectincDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Vitronectin of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
VitronectinELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exists in either a single chain form or a cleaved, two chain form held together by a disulfide bond. Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Because of its ability to bind platelet glycoproteins and mediate platelet adhesion and aggregation at sites of vascular injury, vitronectin has become an important mediator in the pathogenesis of coronary atherosclerosis. As a multifunctional protein with a multiple binding domain, Vitronectin interacts with a variety of plasma and cell proteins. Vitronectin binds multiple ligands, including the soluble vitronectin receptor. It may be an independent predictor of adverse cardiovascular outcomes following acute stenting. Accordingly, Vitronectin is suggested to be involved in hemostasis, cell migration, as well as tumor malignancy.