Anti-BCRP / ABCG2 Antibody

1/2
Price:
Size:
Number:

Anti-BCRP / ABCG2 Antibody (Rabbit Polyclonal 抗体) 产品信息

产品名称
Anti-BCRP / ABCG2 Antibody
经验证的应用
IHC-P
交叉反应
Reacts with: Mouse
特异性
Mouse BCRP / ABCG2
免疫原
A synthetic peptide corresponding to the center region of the Mouse ABCG2
制备方法
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Mouse ABCG2, and purified by antigen affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-BCRP / ABCG2 Antibody (Rabbit Polyclonal 抗体) 经验证的应用

应用 推荐稀释比/用量
IHC-P 1:2000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-BCRP / ABCG2 Antibody (Rabbit Polyclonal 抗体) 图片

Immunochemical staining of mouse ABCG2 in mouse kidney with rabbit polyclonal antibody at 1:5000 dilution, formalin-fixed paraffin embedded sections.
Immunochemical staining of mouse ABCG2 in mouse liver with rabbit polyclonal antibody at 1:5000 dilution, formalin-fixed paraffin embedded sections.

Anti-BCRP / ABCG2 Antibody: 别称

Anti-ABC15 Antibody; Anti-ABCP Antibody; Anti-AI428558 Antibody; Anti-BCRP Antibody; Anti-Bcrp1 Antibody; Anti-MXR Antibody; Anti-MXR1 Antibody

BCRP / ABCG2 背景信息

ATP-binding cassette subfamily G member 2 (ABCG2), a member of the ABC transporter superfamily proteins. the expression of ABCG2 is related to tumorigenic cancer stem cells (CSC) in several cancers, mediates multidrug resistance (MDR) by transporting substrate anticancer drugs out of cancer cells and decreasing their intracellular accumulation. ABCB1 and ABCG2 are efflux transporters which have a major impact on the pharmacological behavior of numerous drugs. They are expressed in the intestine, liver, kidney, BBB and placenta. It has become evident that ABCB1 and ABCG2 modify the pharmaco/toxicokinetics in the placenta and fetus and may consequently affect the outcome of pregnancy.
全称
ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
添加购物车成功! 添加购物车失败!请再次尝试 正在更新购物车,请稍后