Anti-BMP-2 Antibody

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Anti-BMP-2 Antibody (Mouse Monoclonal 抗体) 产品信息

产品名称
Anti-BMP-2 Antibody
经验证的应用
ELISA(Det)
交叉反应
Reacts with: Human
特异性
Human BMP-2
免疫原
Recombinant Human BMP-2 Protein (Catalog#10426-HNAE)
制备方法
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BMP-2 (rh BMP-2 ; Catalog#10426-HNAE; NP_001191.1; Gln283-Arg396). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
来源
Monoclonal Mouse IgG2a Clone #03
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-BMP-2 Antibody (Mouse Monoclonal 抗体) 经验证的应用

Notes
ELISA(Det): This antibody will detect Human BMP-2 in ELISA pair set (Catalog: # SEK10426). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 10426-MM23).
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-BMP-2 Antibody: 别称

Anti-BDA2 Antibody; Anti-BDA2A Antibody; Anti-BMP-2 Antibody; Anti-BMP2A Antibody

BMP-2 背景信息

BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.
全称
bone morphogenetic protein 2
参考文献
  • Jiao X, et al. (2007) Heparan sulfate proteoglycans (HSPGs) modulate BMP-2 osteogenic bioactivity in C2C12 cells. J Biol Chem. 282(2):1080-6.
  • Michon F, et al. (2008) BMP-2 and BMP-7 play antagonistic roles in feather induction. Development 135 (16):2797-805.
  • Heterologous Secretory Expression and Characterization of Dimerized Bone Morphogenetic Protein 2 in Bacillus subtilis
    Author
    Hanif, MU;Gul, R;Hanif, MI;Hashmi, AA;
    Year
    2017
    Journal
    BioMed Research International
    Application
    WB
  • Small Ubiquitin-Like Modifier Protein 3 Enhances the Solubilization of Human Bone Morphogenetic Protein 2 in E. coli
    Author
    Hanif, MU;Yaseen, A;Gul, R;Mirza, MU;Nawaz, MH;Ahmed, SS;Aziz, S;Chaudhary, S;Khan, AA;Shoaib, M;
    Year
    2018
    Journal
    Appl. Biochem. Biotechnol.
    Application
    WB
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