LILRB3 (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)

All LILRB3 reagents are produced in house and quality controlled, including 12 LILRB3 Antibody, 1 LILRB3 ELISA, 13 LILRB3 Gene, 3 LILRB3 Lysate, 4 LILRB3 Protein, 2 LILRB3 qPCR. All LILRB3 reagents are ready to use.

LILRB3 Protein (4)

    LILRB3 Antibody (12)

      LILRB3 ELISA 试剂盒(即用型)& ELISA 抗体对套装(非即用型)(1)

      LILRB3 cDNA Clone (13)

      BC112198.1

      克隆载体 cDNA 产品

      In lentiviral vector

      LILRB3 Lysate (3)

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        LILRB3 分子背景

        Leukocyte immunoglobulin-like receptor subfamily B member 3, also known as Leukocyte immunoglobulin-like receptor 3, Immunoglobulin-like transcript 5, Monocyte inhibitory receptor HL9, CD85 antigen-like family member A, CD85a and LILRB3, is a single-pass type I membrane protein which belongs to the leukocyte receptor cluster (LRC) present on 19q13.4. LILRB3 / CD85a contains fourIg-like C2-type (immunoglobulin-like) domains. LILRB3 / CD85a contains three copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. LILRB3 / CD85a is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found.

        LILRB3 参考文献

        • Huang,J. et al., 2010, J Virol. 84 (18): 9463-71.
        • Arm J.P. et al., 1997, J. Immunol. 159:2342-2349.
        • Wende H. et al., 2000, Immunogenetics 51:703-713.
        • Yu L.-R. et al., 2007,J. Proteome Res. 6:4150-4162.

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