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人 CD155 / PVR / NECL5 蛋白

产品数据评论实验方法
反应性: Human  
应用 : FCM  
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10109-MM09-A-25
10109-MM09-A-100
25 Test 
100 Tests 
Add to Cart
反应性: Human  
应用 : FCM  
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10109-MM09-P-25
10109-MM09-P-100
25 Test 
100 Tests 
Add to Cart
反应性: Human  
应用 : FCM  IF  ICC/IF  
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10109-MM09-F-25
10109-MM09-F-100
25 Test 
100 Tests 
Add to Cart
反应性: Human  
应用 : FCM  
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10109-MM09-50
10109-MM09-200
10109-MM09-100
50 µg 
200 µg 
100 µg 
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反应性: Human  
应用 : ELISA  WB  
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10109-RP01-400
10109-RP01-200
10109-RP01-100
400 µg 
200 µg 
100 µg 
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反应性: Human  
应用 : ELISA  WB  
  • Slide 1
10109-MM11-50
10109-MM11-100
50 µg 
100 µg 
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反应性: Human  
应用 : ELISA  WB  IP  
  • Slide 1
  • Slide 1
10109-R114-50
10109-R114-100
50 µg 
100 µg 
Add to Cart
反应性: Human  
应用 : ELISA  WB  IP  
  • Slide 1
  • Slide 1
10109-RP02-50
10109-RP02-200
10109-RP02-100
50 µg 
200 µg 
100 µg 
Add to Cart
反应性: Mouse  
应用 : FCM  
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50259-R305-C-25
50259-R305-C-100
25 Test 
100 Tests 
Add to Cart
反应性: Mouse  
应用 : FCM  
  • Slide 1
  • Slide 1
50259-R305-F-25
50259-R305-F-100
25 Test 
100 Tests 
Add to Cart
反应性: Mouse  
应用 : FCM  
  • Slide 1
  • Slide 1
50259-R305-P-25
50259-R305-P-100
25 Test 
100 Tests 
Add to Cart
反应性: Mouse  
应用 : FCM  
  • Slide 1
  • Slide 1
50259-R305-A-25
50259-R305-A-100
25 Test 
100 Tests 
Add to Cart
反应性: Mouse  
应用 : ELISA  
    50259-R001-50
    50259-R001-100
    50 µg 
    100 µg 
    Add to Cart
    反应性: Mouse  
    应用 : ELISA  
      50259-RP02-50
      50259-RP02-200
      50259-RP02-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      反应性: Mouse  
      应用 : ELISA  
        50259-RP01-400
        50259-RP01-200
        50259-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart
        反应性: Mouse  
        应用 : ELISA  
          50259-R501-50
          50259-R501-100
          50 µg 
          100 µg 
          Add to Cart
          反应性: Mouse  
          应用 : FCM  IF  ICC/IF  
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          • Slide 1
          50259-R305-50
          50259-R305-100
          50 µg 
          100 µg 
          Add to Cart
          反应性: Rat  
          应用 : ELISA  
            80007-R026-50
            80007-R026-100
            50 µg 
            100 µg 
            Add to Cart
            反应性: Rat  
            应用 : ELISA  
              80007-RP01-400
              80007-RP01-200
              80007-RP01-100
              400 µg 
              200 µg 
              100 µg 
              Add to Cart
              反应性: Rat  
              应用 : ELISA  
                80007-RP02-50
                80007-RP02-200
                80007-RP02-100
                50 µg 
                200 µg 
                100 µg 
                Add to Cart
                反应性: Rat  
                应用 : ELISA  
                  80007-MM06-50
                  80007-MM06-200
                  80007-MM06-100
                  50 µg 
                  200 µg 
                  100 µg 
                  Add to Cart
                  反应性: Rhesus  
                  应用 : ELISA  
                    90005-RP01-400
                    90005-RP01-200
                    90005-RP01-100
                    400 µg 
                    200 µg 
                    100 µg 
                    Add to Cart
                    反应性: Rhesus  
                    应用 : ELISA  
                      90005-RP02-50
                      90005-RP02-200
                      90005-RP02-100
                      50 µg 
                      200 µg 
                      100 µg 
                      Add to Cart
                      反应性: Rhesus  
                      应用 : ELISA  WB  
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                      90005-MM06-50
                      90005-MM06-200
                      90005-MM06-100
                      50 µg 
                      200 µg 
                      100 µg 
                      Add to Cart

                      HP100017 

                      CD155/PVR 蛋白Related Products

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                      CD155/PVR protein 研究背景

                      CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhension, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.

                      Immune Checkpoint
                      Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: IP Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB Antibodies
                      Immune Checkpoint Proteins
                      Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

                      Immunotherapy   Cancer Immunotherapy   Targeted Therapy

                       CD155/PVR protein 参考资料
                    • Freistadt MS, et al. (2000) Hematopoietic cells from CD155-transgenic mice express CD155 and support poliovirus replication ex vivo. Microb Pathog. 29(4): 203-12.
                    • Sato T, et al. (2004) Involvement of heterophilic trans-interaction of Necl-5/Tage4/PVR/CD155 with nectin-3 in formation of nectin- and cadherin-based adherens junctions. Genes Cells. 9(9): 791-9.
                    • Kakunaga S, et al. (2004) Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/poliovirus receptor/CD155 through the Ras-Raf-MEK-ERK signaling. J Biol Chem. 279(35): 36419-25.
                    • Sato T, et al. (2005) Common signaling pathway is used by the trans-interaction of Necl-5/Tage4/PVR/CD155 and nectin, and of nectin and nectin during the formation of cell-cell adhesion. Cancer Sci. 96(9): 578-89.
                    • Minami Y, et al. (2007) Involvement of up-regulated Necl-5/Tage4/PVR/CD155 in the loss of contact inhibition in transformed NIH3T3 cells. Biochem Biophys Res Commun. 352(4): 856-60.
                    • 请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”