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小鼠 FDPS / Farnesyl Diphosphate Synthase 基因ORF全长cDNA克隆(表达载体), N-Myc 标签

产品数据评论实验方法
表达宿主: E. coli  
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13229-H07E-50
13229-H07E-20
50 µg 
20 µg 
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表达宿主: E. coli  
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51224-M07E-20
51224-M07E-100
20 µg 
100 µg 
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反应性: Human  
应用 : FCM  
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13229-R005-F-25
13229-R005-F-100
25 Test 
100 Tests 
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反应性: Human  
应用 : ELISA  WB  FCM  IF  IP  ICC/IF  
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13229-R005-50
13229-R005-100
50 µg 
100 µg 
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反应性: Human  
应用 : ELISA  WB  IP  
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13229-T52-50
13229-T52-200
13229-T52-100
50 µg 
200 µg 
100 µg 
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反应性: Human  
应用 : ELISA  
    13229-RP01-400
    13229-RP01-200
    13229-RP01-100
    400 µg 
    200 µg 
    100 µg 
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    反应性: Human  
    应用 : WB  IP  
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    13229-R002-50
    13229-R002-100
    50 µg 
    100 µg 
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    反应性: Mouse  
    应用 : 
      51224-R115-50
      51224-R115-100
      50 µg 
      100 µg 
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      反应性: Mouse  
      应用 : WB  IHC-P  IP  
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      51224-T44-50
      51224-T44-200
      51224-T44-100
      50 µg 
      200 µg 
      100 µg 
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      反应性: Mouse  
      应用 : ELISA  
        51224-RP01-400
        51224-RP01-200
        51224-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart
        反应性: Mouse  
        应用 : ELISA  
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        51224-R003-50
        51224-R003-100
        50 µg 
        100 µg 
        Add to Cart

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        FDPS / Farnesyl Diphosphate Synthase cdna-clone 研究背景

        Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions as key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate, a precurcor for several classes of essential metabolites. FDPS catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Functions of FDPS may be inactivated by interferon-induced RSAD2. This inactivation may result of disruption of lipid rafts at the plasma membrane, and thus have an antiviral effect since many enveloped viruses need lipid rafts to bud efficiently out of the cell.

        小鼠 FDPS / Farnesyl Diphosphate Synthase cdna-clone 参考资料
      • Pjetursson BE, et al. (2007) Comparison of survival and complication rates of tooth-supported fixed dental prostheses (FDPs) and implant-supported FDPs and single crowns (SCs). Clin Oral Implants Res. 3:97-113.
      • Eschbach S, et al. (2009) Clinical evaluation of all-ceramic posterior three-unit FDPs made of In-Ceram Zirconia. Int J Prosthodont. 22(5):490-2.
      • Moshage HJ, et al. (1990) Differential effects of endotoxin and fibrinogen degradation products (FDPS) on liver synthesis of fibrinogen and albumin: evidence for the involvement of a novel monokine in the stimulation of fibrinogen synthesis induced by FDPS. Int J Biochem. 22(12): 1393-400.
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