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人 JAML / AMICA 蛋白 (His 标签)

产品数据评论实验方法
反应性: Human  
应用 : FCM  
  • Slide 1
  • Slide 1
10120-MM02-F-25
10120-MM02-F-100
25 Test 
100 Tests 
Add to Cart
反应性: Human  
应用 : FCM  
  • Slide 1
  • Slide 1
10120-MM02-P-25
10120-MM02-P-100
25 Test 
100 Tests 
Add to Cart
反应性: Human  
应用 : FCM  
  • Slide 1
10120-MM02-A-25
10120-MM02-A-100
25 Test 
100 Tests 
Add to Cart
反应性: Human  
应用 : 
    10120-MM05-50
    10120-MM05-200
    10120-MM05-100
    10120-MM05-1
    50 µg 
    200 µg 
    100 µg 
    1 mg 
    Add to Cart
    反应性: Human  
    应用 : ELISA  
      10120-RP02-50
      10120-RP02-200
      10120-RP02-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      反应性: Human  
      应用 : 
        10120-MM06-50
        10120-MM06-200
        10120-MM06-100
        10120-MM06-1
        50 µg 
        200 µg 
        100 µg 
        1 mg 
        Add to Cart
        反应性: Human  
        应用 : ELISA  
          10120-RP01-400
          10120-RP01-200
          10120-RP01-100
          400 µg 
          200 µg 
          100 µg 
          Add to Cart
          反应性: Human  
          应用 : ELISA  
            10120-MM08-50
            10120-MM08-200
            10120-MM08-100
            50 µg 
            200 µg 
            100 µg 
            Add to Cart
            反应性: Human  
            应用 : FCM  
            • Slide 1
            10120-MM02-50
            10120-MM02-200
            10120-MM02-100
            50 µg 
            200 µg 
            100 µg 
            Add to Cart

            JAML/AMICA1 蛋白Related Products

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            JAML/AMICA1 protein 研究背景

            Junctional adhesion molecules (JAMs) are endothelial and epithelial adhesion molecules involved in the recruitment of circulating leukocytes to inflammatory sites. JAML (Junctional adhesion molecule-like), also known as AMICA1 (Adhesion molecule interacting with CXADR antigen 1), a protein related to the JAM family, is restricted to leukocytes and promotes their adhesion to endothelial cells. It contains 2 extracellular immunoglobulin-like domains, a transmembrane segment, and a cytoplasmic tail involved in activation signaling. Monocytic JAML/AMICA1 plays a critical role in regulating monocyte transendothelial migration (TEM) probably via binding to the endothelial coxsackie and adenovirus receptor (CAR) and other tight junction-associated adhesive molecules. The Expression of JAML/AMICA1 is restricted to the hematopoietic tissues with the exception of liver. JAML may function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, JAML/AMICA1 also enhances myeloid leukemia cell adhesion to endothelial cells.

             JAML/AMICA1 protein 参考资料
          • Moog-Lutz C, et al. (2003) JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells. Blood. 102(9): 3371-8.
          • Luissint AC, et al. (2008) JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation. J Cell Biol. 183(6): 1159-73.
          • Guo YL, et al. (2009) Role of junctional adhesion molecule-like protein in mediating monocyte transendothelial migration. Arterioscler Thromb Vasc Biol. 29(1): 75-83.
          • 请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”