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小鼠 AK4 / Adenylate Kinase 4 / AK3L1 基因ORF全长cDNA克隆(表达载体), N-Flag 标签

产品数据评论实验方法
表达宿主: Baculovirus-Insect Cells  
  • Slide 1
12406-H20B-50
50 µg 
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表达宿主: Baculovirus-Insect Cells  
  • Slide 1
12406-HNCB-50
50 µg 
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反应性: Human  
应用 : FCM  
  • Slide 1
12406-MM09-P-25
12406-MM09-P-100
25 Test 
100 Tests 
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反应性: Human  
应用 : ELISA  WB  IP  
  • Slide 1
  • Slide 1
12406-RP02-50
12406-RP02-200
12406-RP02-100
50 µg 
200 µg 
100 µg 
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反应性: Human  
应用 : ELISA  WB  IP  
  • Slide 1
  • Slide 1
12406-MM08-50
12406-MM08-200
12406-MM08-100
50 µg 
200 µg 
100 µg 
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反应性: Human  
应用 : WB  IF  IP  ICC/IF  
  • Slide 1
  • Slide 1
  • Slide 1
12406-R010-50
12406-R010-100
50 µg 
100 µg 
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反应性: Human  
应用 : FCM  IF  ICC/IF  
  • Slide 1
  • Slide 1
12406-MM09-50
12406-MM09-200
12406-MM09-100
50 µg 
200 µg 
100 µg 
Add to Cart
反应性: Human  
应用 : ELISA  IP  
  • Slide 1
12406-R014-50
12406-R014-100
50 µg 
100 µg 
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反应性: Human  
应用 : ELISA  
    12406-MM04-50
    12406-MM04-200
    12406-MM04-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    反应性: Human  
    应用 : ELISA  
      12406-RP01-400
      12406-RP01-200
      12406-RP01-100
      400 µg 
      200 µg 
      100 µg 
      Add to Cart

      AK4 / Adenylate Kinase 4 / AK3L1 cDNARelated Products

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      AK4 / Adenylate Kinase 4 / AK3L1 cdna-clone 研究背景

      Adenylate kinase isoenzyme 4, mitochondrial, also known as ATP-AMP transphosphorylase, Adenylate kinase 3-like, AK4 and AK3L1, is a member the adenylate kinase family. AK4 / AK3L1 is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. AK4 / AK3L1 catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. It may also be active with GTP. Adenylate kinase 4 ( AK4 / AK3L1 ) is a unique member with no enzymatic activity in the adenylate kinase (AK) family although it shares high sequence homology with other AKs. It remains unclear what physiological function AK4 might play or why it is enzymatically inactive. AK4 / AK3L1 retains the capability of binding nucleotides. It has a glutamine residue instead of a key arginine residue in the active site well conserved in other AKs. The enzymatically inactive AK4 is a stress responsive protein critical to cell survival and proliferation. AK4 / AK3L1 is likely that the interaction with the mitochondrial inner membrane protein ANT is important for AK4 to exert the protective benefits to cells under stress. AK4 / AK3L1 also acts on the specific mechanism of energy metabolism rather than control of the homeostasis of the ADP pool ubiquitously.

      小鼠 AK4 / Adenylate Kinase 4 / AK3L1 cdna-clone 参考资料
      请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”