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人 CCL17/TARC 基因ORF全长cDNA克隆(表达载体), C-Flag 标签

产品数据评论实验方法
表达宿主: Baculovirus-Insect Cells  
  • Slide 1
10233-H08B-50
10233-H08B-20
50 µg 
20 µg 
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表达宿主: Baculovirus-Insect Cells  
  • Slide 1
10233-HNAB-50
10233-HNAB-20
50 µg 
20 µg 
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表达宿主: Baculovirus-Insect Cells  
  • Slide 1
50046-MNAB-50
50046-MNAB-20
50 µg 
20 µg 
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表达宿主: Baculovirus-Insect Cells  
  • Slide 1
90077-C08B-50
90077-C08B-20
50 µg 
20 µg 
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反应性: Human  
应用 : ELISA  
    10233-RP01-400
    10233-RP01-200
    10233-RP01-100
    400 µg 
    200 µg 
    100 µg 
    Add to Cart
    反应性: Human  
    应用 : ELISA  
      10233-T16-50
      10233-T16-200
      10233-T16-100
      50 µg 
      200 µg 
      100 µg 
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      反应性: Human  
      应用 : ELISA  
        10233-MM03-50
        10233-MM03-200
        10233-MM03-100
        50 µg 
        200 µg 
        100 µg 
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        反应性: Human  
        应用 : ELISA  
          10233-RP02-50
          10233-RP02-200
          10233-RP02-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          反应性: Mouse  
          应用 : ELISA  
            50046-RP01-400
            50046-RP01-200
            50046-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart

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            CCL17/TARC cdna-clone 研究背景

            Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4.

             CCL17/TARC cdna-clone 参考资料
          • Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.
          • Cocchi F, et al. (1995) Identification of RANTES, MIP-1a, and MIP-1b as the major HIV-suppressive factor produced by CD8+ T cells. Science. 270 (5243): 1811-5.
          • Morita A, et al. (2002). Evaluation of human thymus and activation-regulated chemokine concentrations in blood using a new sandwich ELISA based on monoclonal antibodies. Clin Chim Acta. 322 (1-2): 67-75.
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