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人 Vasorin 基因ORF全长cDNA克隆(表达载体), N-HA 标签

产品数据评论实验方法
表达宿主: Human Cells  
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13854-H08H-50
13854-H08H-100
50 µg 
100 µg 
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反应性: Human  
应用 : 
    13854-R010-50
    13854-R010-100
    13854-R010-1
    50 µg 
    100 µg 
    1 mg 
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    反应性: Human  
    应用 : ELISA  
      13854-RP01-400
      13854-RP01-200
      13854-RP01-100
      400 µg 
      200 µg 
      100 µg 
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      反应性: Human  
      应用 : ELISA  
        13854-R101-50
        13854-R101-100
        13854-R101-1
        50 µg 
        100 µg 
        1 mg 
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        反应性: Human  
        应用 : ELISA  
          13854-MM04-50
          13854-MM04-200
          13854-MM04-100
          50 µg 
          200 µg 
          100 µg 
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          反应性: Human  
          应用 : ELISA  
            13854-T16-50
            13854-T16-200
            13854-T16-100
            50 µg 
            200 µg 
            100 µg 
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            Vasorin cdna-clone 研究背景

            Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular smooth muscle cells, and that its expression is developmentally regulated. vasorin It directly binds to transforming growth factor (TGF)-β and attenuates TGF-β signaling in vitro. This suggests that down-regulation of vasorin expression contributes to neointimal formation after vascular injury and that vasorin modulates cellular responses to pathological stimuli in the vessel wall.

             Vasorin cdna-clone 参考资料
          • Gerhard DS, et al. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 14(10B):2121-7.
          • Kim W, et al. (2011) Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell. 44(2):325-40.
          • Lee KA, et al. (2011) Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. J Biol Chem. 286(48):41530-8.
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